136523-34-7

Upstream product

• 135086-49-6 (S)-4-[(S)-((2R,3R,4S)-3,4-Dihydroxy-5-oxo-tetrahydro-furan-2-yl)-trimethylsilanyloxy-methyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 136598-84-0 (S)-2,2-Dimethyl-4-((2S,3S,4S,5S,6R)-3,4,5,6-tetraacetoxy-tetrahydro-pyran-2-yl)-oxazolidine-3-carboxylic acid tert-butyl ester 
• 135086-53-2 Acetic acid (2S,3S,4S,5S,6R)-4,5,6-triacetoxy-2-((S)-1-tert-butoxycarbonylamino-2-hydroxy-ethyl)-tetrahydro-pyran-3-yl ester 
• 136597-85-8 (S)-2,2-Dimethyl-4-[(S)-((2S,3S,4S)-5-oxo-3,4-bis-trimethylsilanyloxy-tetrahydro-furan-2-yl)-trimethylsilanyloxy-methyl]-oxazolidine-3-carboxylic acid tert-butyl ester 
• 135086-47-4 (S)-4-[(S)-((2S,3S,4S)-5-Hydroxy-3,4-bis-trimethylsilanyloxy-tetrahydro-furan-2-yl)-trimethylsilanyloxy-methyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 135086-48-5 (S)-2,2-Dimethyl-4-[(S)-((R)-5-oxo-2,5-dihydro-furan-2-yl)-trimethylsilanyloxy-methyl]-oxazolidine-3-carboxylic acid tert-butyl ester 
• 135086-51-0 (S)-2,2-Dimethyl-4-((2S,3R,4S,5S)-3,4,5,6-tetrahydroxy-tetrahydro-pyran-2-yl)-oxazolidine-3-carboxylic acid tert-butyl ester 
• 131613-94-0 6,7-N,O-Isopropylidene-6-<(tert-butoxycarbonyl)amino>-2,3,6-trideoxy-L-ribo-hept-2-enono-1,4-lactone 
• 131613-93-9 6,7-N,O-Isopropylidene-6-<(tert-butoxycarbonyl)amino>-2,3,6-trideoxy-L-arabino-hept-2-enono-1,4-lactone 
• 102308-32-7 (4S)-4-formyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 186581-53-3 diazomethane 
• 135086-54-3 (R)-tert-Butoxycarbonylamino-((2S,3S,4S,5S,6R)-3,4,5,6-tetraacetoxy-tetrahydro-pyran-2-yl)-acetic acid 

Relevant academic research and scientific papers

Total Synthesis of 6-Deoxy-6-aminoheptopyranuronic Acid Derivatives

Two enantio couples of terminal C-glycoyranosyl α-amino acids, namely the aminopyranuronic acid, L-9, D-9 and L-10, D-10, hve been synthesized from serine-derived pair L-2, D-2 by exploiting enantiomerically pure butenolide intermediates 3 and 4.The key synthetic steps involved the sequential antiselective cis dihydroxylation of the butenolide double bond and the clean furaose-to-pyranose ring expansion to construct the sugar skeleton with the proper stereochemistry.In our best performance, homogeneous L-9 was prepared from L-2 in four steps and 10 reactions in 20percent overall yield.