131615-77-5

Upstream product

• 63598-31-2 methyl 4,6-O-(R)-benzylidene-2-deoxy-α-D-erythrohexopyranosid-3-ulose 

Downstream Products

• 116663-00-4 Methyl 3-amino-4,6-O-benzylidene-2,3-dideoxy-β-D-ribo-hexopyranoside 
• 114047-66-4 (2R,4aR,6R,7S,8aR)-7-(1-Hydroxy-propyl)-6-methoxy-2-phenyl-tetrahydro-pyrano[3,2-d][1,3]dioxin-8-one 
• 139757-39-4 methyl 4,6-O-benzylidene-2-deoxy-3-oximino-β-D-erythro-hexopyranoside 
• 6752-52-9 (2R,6S,8S)-6-Methoxy-8-methyl-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-ol 

Relevant academic research and scientific papers

Carbohydrate-derived partners display remarkably high stereoselectivity in aldol coupling reactions

Aldol condensation between 3-keto and aldehyde sugars have been studied. The enolate 3 reacts with aldehydes preferentially from the β-face to give axial C2 condensation products. However, if the reaction conditions are not controlled properly some C2 epi

A PRACTICABLE SYNTHESIS OF N-TRIFLUOROACETYL-L-DAUNOSAMINE FROM D-GlUCOSE

A synthesis of the N-trifluoroacetyl derivative of L-daunosamine, the glucidic component of adriamycin and daunomycin, two antibiotics with proved antineoplastic activity, is described starting from D-glucose, an inexpensive carbohydrate source.The synthetic sequence involves the stereoselective introduction of the C(3) amino group and the inversion at C(5), obtained by the stereospecific hydrogenation of a 5-methylenepyranose derivative, to flip from the D over the L series.