139757-39-4Relevant academic research and scientific papers
Experimental and Theoretical (AM1) Studies on Photoaddition Reactions of 3-Nitro-2-enopyranoside Derivatives
Sakakibara, Tohru,Matuo, Ichiro,Takaide, Aya,Nakamura, Takanori,Seta, Akinori
, p. 177 - 180 (2007/10/02)
Irradiation of 3-nitro-α- and β-D-erythro-hex-2-enopyranoside derivatives in methanol, ethanol, and isopropanol with high pressure Hg lamp gave the adducts in moderate yields.The stereoselectivities calculated by AM1 calculation by the use of model compou
A PRACTICABLE SYNTHESIS OF N-TRIFLUOROACETYL-L-DAUNOSAMINE FROM D-GlUCOSE
Crugnola, Angelo,Lombardi, Paolo,Gandolfi, Carmelo,Arcamone, Federico
, p. 395 - 400 (2007/10/02)
A synthesis of the N-trifluoroacetyl derivative of L-daunosamine, the glucidic component of adriamycin and daunomycin, two antibiotics with proved antineoplastic activity, is described starting from D-glucose, an inexpensive carbohydrate source.The synthetic sequence involves the stereoselective introduction of the C(3) amino group and the inversion at C(5), obtained by the stereospecific hydrogenation of a 5-methylenepyranose derivative, to flip from the D over the L series.
