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N-(2-(2-(5-chloropyridin-2-ylamino)-2-oxoethylthio)benzo[d]thiazol-6-yl)-2-methoxybenzamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1316196-75-4

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1316196-75-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1316196-75-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,6,1,9 and 6 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1316196-75:
(9*1)+(8*3)+(7*1)+(6*6)+(5*1)+(4*9)+(3*6)+(2*7)+(1*5)=154
154 % 10 = 4
So 1316196-75-4 is a valid CAS Registry Number.

1316196-75-4Downstream Products

1316196-75-4Relevant academic research and scientific papers

Synthesis and biological evaluation of novel benzothiazole-2-thiol derivatives as potential anticancer agents

Shi, Xuan-Hong,Wang, Zhao,Xia, Yong,Ye, Ting-Hong,Deng, Mei,Xu, You-Zhi,Wei, Yu-Quan,Yu, Luo-Ting

, p. 3933 - 3944 (2012/07/14)

A series of novel benzothiazole-2-thiol derivatives were synthesized and their structures determined by 1H-NMR, 13C-NMR and HRMS (ESI). The effects of all compounds on a panel of different types of human cancer cell lines were investigated. Among them, pyridinyl-2-amine linked benzothiazole-2-thiol compounds 7d, 7e, 7f and 7i exhibited potent and broad-spectrum inhibitory activities. Compound 7e displayed the most potent anticancer activity on SKRB-3 (IC50 = 1.2 nM), SW620 (IC50 = 4.3 nM), A549 (IC50 = 44 nM) and HepG2 (IC50 = 48 nM) and was found to induce apoptosis in HepG2 cancer cells.

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