13162-24-8 Usage
General Description
4-Chloro-6-methyl-5-nitro-pyrimidin-2-amine is a chemical compound with the molecular formula C5H5ClN4O2. It is a member of the pyrimidine family and is characterized by the presence of a chlorine atom, a methyl group, and a nitro group attached to a pyrimidine ring. 4-chloro-6-methyl-5-nitro-pyrimidin-2-amine has potential applications in the pharmaceutical industry, particularly in the development of antiviral and antibacterial drugs due to its ability to inhibit the growth and replication of certain pathogens. Its unique structure and properties make it a valuable research subject for the development of new therapeutics. Additionally, it is also used as a research reagent and in chemical synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 13162-24-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,1,6 and 2 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 13162-24:
(7*1)+(6*3)+(5*1)+(4*6)+(3*2)+(2*2)+(1*4)=68
68 % 10 = 8
So 13162-24-8 is a valid CAS Registry Number.
InChI:InChI=1/C5H8ClN5/c1-9-4-2(7)3(6)10-5(8)11-4/h7H2,1H3,(H3,8,9,10,11)
13162-24-8Relevant articles and documents
SAR studies on a novel series of human cytomegalovirus primase inhibitors
Chen,Adrian,Cushing,DiMaio,Liang,Mayorga,Miao,Peterson,Powers,Spector,Stein,Wright,Xu,Ye,Jaen
, p. 2188 - 2192 (2008/02/03)
A novel series of imidazolylpyrimidines were found to possess inhibitory activity against the human CMV UL70 primase. Extensive SAR studies on an HTS lead led to potent, orally bioavailable compounds with anti-CMV IC50 values of 150 nM in both
Structure-Activity Relations. Part 12. Antibacterial Activity of a Series of 2,4-Diamino-6-substituted 5-(4-pyridylmethylamino)pyrimidines and 2,4-Diamino-5-(4-substituted benzylamino)pyrimidines.
Bowden, Keith,Bright, Andrew C.
, p. 514 - 539 (2007/10/02)
A series of 6-substituted 2,4-diamino-5-(4-pyridylamino)pyrimidines and of 2,4-diamino-5-(4-substituted benzylamino)pyrimidines has been prepared.Their antibacterial activity towards L. casei, S. aureus and E. coli has been investigated.These activities have been successfully correlated by Hansch-type relations.Dependence on both lipophilicity and electronic (polar) factors has been found.The results are related to the structure and interactions with the receptor.
