2829-59-6

Basic information

• Product Name: 6-methyl-5-nitro-pyrimidine-2,4-diamine
• Synonyms: 6-methyl-5-nitro-pyrimidine-2,4-diamine;2,4-Diamino-6-methyl-5-nitropyrimidine;2,4-Pyrimidinediamine, 6-methyl-5-nitro-;(2-amino-6-methyl-5-nitro-pyrimidin-4-yl)amine;6-methyl-2,4-diamino-5-nitropyrimidine
• CAS NO: 2829-59-6
• Molecular Formula: C₅H₇N₅O₂
• Molecular Weight: 169.14
• Mol File: 2829-59-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 478.5 °C at 760 mmHg
• Flash Point: 243.2 °C
• Appearance: /
• Density: 1.558 g/cm³
• Vapor Pressure: 2.56E-09mmHg at 25°C
• Refractive Index: 1.706
• CAS DataBase Reference: 6-methyl-5-nitro-pyrimidine-2,4-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methyl-5-nitro-pyrimidine-2,4-diamine(2829-59-6)
• EPA Substance Registry System: 6-methyl-5-nitro-pyrimidine-2,4-diamine(2829-59-6)

Safety Data

• Hazardous Substances Data: 2829-59-6(Hazardous Substances Data)

Usage

General Description

6-methyl-5-nitro-pyrimidine-2,4-diamine is a chemical compound with the molecular formula C5H7N5O2. It is a pyrimidine analog that is commonly used in the synthesis of pharmaceuticals and agrochemicals. 6-methyl-5-nitro-pyrimidine-2,4-diamine is known for its antimicrobial properties and is used as an active ingredient in various drugs and pesticides. It works by inhibiting the growth of bacteria and other microorganisms by interfering with their DNA replication and metabolic processes. 6-methyl-5-nitro-pyrimidine-2,4-diamine is a versatile building block in organic chemistry and has a wide range of applications in the pharmaceutical and agricultural industries.

InChI:InChI=1/C5H7N5O2/c1-2-3(10(11)12)4(6)9-5(7)8-2/h1H3,(H4,6,7,8,9)

Upstream product

• 1791-73-7 6-methylpyrimidine-2,4-diamine 
• 13162-24-8 2-amino-4-chloro-5-nitro-6-methylpyrimidine 
• 13162-26-0 2,4-dichloro-6-methyl-5-nitropyrimidine 
• 5600-21-5 2-amino-6-methyl-4-chloropyrimidine 
• 5424-21-5 2,4-dichloro-6-methylpyrimidine 
• 4214-85-1 2-amino-4-hydroxy-6-methyl-5-nitropyrimidine 
• 3977-29-5 2-amino-6-methylpyrimidin-4-ol 
• 7664-41-7 ammonia 
• 100115-65-9 N⁴-benzyloxy-6-methyl-5-nitro-pyrimidine-2,4-diyldiamine 

Downstream Products

• 724762-21-4 N-(4-acetylamino-6-dibromomethyl-5-nitropyrimidin-2-yl)acetamide 
• 724762-07-6 2-benzyl-2-(2,6-diamino-5-nitropyrimidin-4-yl)-3-phenylpropionitrile 
• 724762-06-5 2-(2,6-diamino-5-nitropyrimidin-4-yl)-3-phenylpropionitrile 
• 724762-09-8 3-phenyl-2-(2,5,6-triaminopyrimidin-4-yl)propionitrile 
• 724762-19-0 N-(4-benzoylamino-6-methyl-5-nitropyrimidin-2-yl)benzamide 

Relevant articles and documents

Structure-Activity Relations. Part 12. Antibacterial Activity of a Series of 2,4-Diamino-6-substituted 5-(4-pyridylmethylamino)pyrimidines and 2,4-Diamino-5-(4-substituted benzylamino)pyrimidines.

A series of 6-substituted 2,4-diamino-5-(4-pyridylamino)pyrimidines and of 2,4-diamino-5-(4-substituted benzylamino)pyrimidines has been prepared.Their antibacterial activity towards L. casei, S. aureus and E. coli has been investigated.These activities have been successfully correlated by Hansch-type relations.Dependence on both lipophilicity and electronic (polar) factors has been found.The results are related to the structure and interactions with the receptor.