131667-52-2Relevant academic research and scientific papers
REGIOSELECTIVE INTRODUCTION OF ALKYL GROUPS TO THE POSITION α OR γ TO NITROGEN ATOM OF PIPERIDINE SKELETONS USING ANODIC OXIDATION IN A KEY STEP
Shono, Tatsuya,Terauchi, Jun,Ohki, Yoshihisa,Matsumura, Yoshihiro
, p. 6385 - 6386 (2007/10/02)
β,γ-Unsaturated N-alkoxycarbonyl-α-methoxypiperidines, which were prepared from N-alkoxypiperidines by using anodic oxidation in a key step, were regioselectively alkylated at the α-position by using Grignard reagents in the presence of BF3*Et2O, whereas in the presence of CuBr, the alkylation took place at the γ-position.
