Welcome to LookChem.com Sign In|Join Free

CAS

  • or
(+/-)-3-Benzylproline is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

131669-72-2

Post Buying Request

131669-72-2 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

131669-72-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 131669-72-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,1,6,6 and 9 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 131669-72:
(8*1)+(7*3)+(6*1)+(5*6)+(4*6)+(3*9)+(2*7)+(1*2)=132
132 % 10 = 2
So 131669-72-2 is a valid CAS Registry Number.

131669-72-2Downstream Products

131669-72-2Relevant articles and documents

2-Amino Ketene S,S-Acetals as α-Amino Acid Homoenolate Equivalents. Synthesis of 3-Substituted Prolines and Molecular Structure of 2-(N-Pivaloylpyrrolidin-2-ylidene)-1,3-dithiane

Moss, William O.,Jones, Annette C.,Wisedale, Richard,Mahon, Mary F.,Molloy, Kieran C.,et al.

, p. 2615 - 2624 (2007/10/02)

Allylic deprotonation of the heterocyclic 2-amino ketene S,S-acetal 8a, followed by regioselective γ-alkylation reaction of the resulting organolithium 10 (a proline homoenolate equivalent) with electrophiles, leads to adduct 11.Controlled hydrolytic cleavage of 11 gives a series of 3-substituted prolines, including the conformationally-constrained aspartate and glutamate derivatives, 14e and 14f respectively.The bicyclic thiolactam 18 has been prepared in an attempt to provide an asymmetric variant of organolithium 10 but efforts to generate the requisite ketene N,S-acetal 19 were unsuccessful.Extension of the ketene S,S-acetal chemistry to other ring sizes has been examined within the context of substituted azetidine-2-carboxylates.Condensation of the protected amino ester 20 with AlMe3-HS(CH2)3SH was complicated, however, by the reactivity of the four-membered ring and led to the ring-opened adduct 24, with none of the required ketene S,S-acetal 22 being observed.

Generation of α-amino acid homoenolate equivalents. Synthesis of 3-substituted prolines

Moss, William O.,Bradbury, Roben H.,Hales, Neil J.,Gallagher, Timothy

, p. 5653 - 5656 (2007/10/02)

Deprotonation of the N-protected aminoketene-S,S-acetal (6) and reaction of allylic anion (7) with electrophiles leads to adducts (8) which have been converted to 3-substituted prolines (11). Conformationally constrained variants (11d) and (11e) of aspartic and glutamic acid have been prepared.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 131669-72-2