1316847-99-0

Basic information

• Product Name: (S)-benzyl 3-(((S)-1-(tert-butoxy)-1-oxo-3-phenylpropan-2-yl)amino)pyrrolidine-1-carboxylate hydrochloride
• CAS NO: 1316847-99-0
• Molecular Weight: 461.001
• Mol File: 1316847-99-0.mol

Chemical Properties

• CAS DataBase Reference: (S)-benzyl 3-(((S)-1-(tert-butoxy)-1-oxo-3-phenylpropan-2-yl)amino)pyrrolidine-1-carboxylate hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-benzyl 3-(((S)-1-(tert-butoxy)-1-oxo-3-phenylpropan-2-yl)amino)pyrrolidine-1-carboxylate hydrochloride(1316847-99-0)
• EPA Substance Registry System: (S)-benzyl 3-(((S)-1-(tert-butoxy)-1-oxo-3-phenylpropan-2-yl)amino)pyrrolidine-1-carboxylate hydrochloride(1316847-99-0)

Safety Data

• Hazardous Substances Data: 1316847-99-0(Hazardous Substances Data)

Upstream product

• 100858-33-1 (3R)-3-hydroxy-pyrrolidine-1-carboxylic acid benzyl ester 
• 501-53-1 benzyl chloroformate 
• 15100-75-1 L-phenylalanine tert-butyl ester hydrochloride 
• 16874-17-2 L-phenylalanine tert-butyl ester 
• 1316847-95-6 (S)-benzyl 3-(((S)-1-(tert-butoxy)-1-oxo-3-phenylpropan-2-yl)amino)pyrrolidine-1-carboxylate 

Downstream Products

• 1316848-07-3 (S)-tert-butyl 3-phenyl-2-((S)-pyrrolidin-3-ylamino)propanoate hydrochloride 
• 1316848-13-1 (S)-5-benzyl-4-(tert-butoxy)-1-((S)-pyrrolidin-3-yl)-1H-pyrrol-2(5H)-one 
• 1316848-21-1 (S)-5-benzyl-4-(tert-butoxy)-1-((S)-1-((S)-2-methyl-5-oxo-2,5-dihydro-1H-pyrrol-3-yl)pyrrolidin-3-yl)-1H-pyrrol-2(5H)-one 
• 1316848-28-8 (S)-5-benzyl-1-((S)-1-((S)-2-benzyl-5-oxo-2,5-dihydro-1H-pyrrol-3-yl)pyrrolidin-3-yl)-4-(tert-butoxy)-1H-pyrrol-2(5H)-one 
• 1316848-10-8 (S)-benzyl 3-((S)-2-benzyl-3-(tert-butoxy)-5-oxo-2,5-dihydro-1H-pyrrol-1-yl)pyrrolidine-1-carboxylate 

Relevant articles and documents

Expanding the scope of oligo-pyrrolinone-pyrrolidines as protein-protein interface mimics

Oligo-pyrrolinone-pyrrolidines (generic structure 1) have the potential to interfere with protein-protein interactions (PPIs), but to reduce this to practice it is necessary to be able to synthesize these structures with a variety of different side chains

Pyrrolinone-pyrrolidine oligomers as universal peptidomimetics

Peptidomimetics 1-3 were prepared from amino acid-derived tetramic acids 7 as the key starting materials. Calculations show that preferred conformations of 1 can align their side-chain vectors with amino acids in common secondary structures more effectively than conformations of 3. A good fit was found for a preferred conformation of 2 (an extended derivative of 1) with a sheet/β-turn/sheet motif.