1316848-57-3

Basic information

• Product Name: 2-(4-fluorophenyl)-1-(trimethylsiloxy)cyclohex-1-ene
• Synonyms: 2-(4-fluorophenyl)-1-(trimethylsiloxy)cyclohex-1-ene
• CAS NO: 1316848-57-3
• Molecular Weight: 264.415
• Mol File: 1316848-57-3.mol

Chemical Properties

• CAS DataBase Reference: 2-(4-fluorophenyl)-1-(trimethylsiloxy)cyclohex-1-ene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-fluorophenyl)-1-(trimethylsiloxy)cyclohex-1-ene(1316848-57-3)
• EPA Substance Registry System: 2-(4-fluorophenyl)-1-(trimethylsiloxy)cyclohex-1-ene(1316848-57-3)

Safety Data

• Hazardous Substances Data: 1316848-57-3(Hazardous Substances Data)

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 59227-02-0 rac-2-(4-fluorophenyl)cyclohexan-1-one 
• 352-34-1 4-fluoro-1-iodobenzene 
• 6651-36-1 1-(Trimethylsilyloxy)cyclohexene 
• 851337-37-6 rac-2-(4-fluoro-phenyl)-cyclohexanol 

Relevant articles and documents

Enantioselective Protonation of Silyl Enol Ethers Catalyzed by a Chiral Pentacarboxycyclopentadiene-Based Bronsted Acid

The enantioselective protonation of silyl enol ethers was realized in the presence of a pentacarboxycyclopenta-1,3-diene-based chiral Bronsted acid catalyst with water as an achiral proton source to give the corresponding α-aryl ketones in good yields and up to 75percent ee.

Chiral sulfinamide/achiral sulfonic acid cocatalyzed enantioselective protonation of enol silanes

The application of chiral sulfinamides and achiral sulfonic acids as a cocatalyst system for enantioselective protonation reactions is described. Structurally simple, easily accessible sulfinamides were found to induce moderate-to-high ee's in the formation of 2-aryl-substituted cycloalkanones from the corresponding trimethylsilyl enol ethers.