1316852-76-2

Upstream product

• 79388-04-8 1,6-diamino-2-oxo-4-phenyl-1,2-dihydropyridine-3,5-dicarbonitrile 
• 1038081-85-4 1-amino-6-(triphenylphosphoranylideneamino)-2-oxo-4-phenyl-1,2-dihydropyridine-3,5-dicarbonitrileiminophosphorane 
• 1038081-88-7 5-oxo-7-phenyl-2-thiol-3,5-dihydro[1,2,4]triazolo[1,5-a]pyridine-6,8-dicarbonitrile 
• 122-03-2 (4-isopropylbenzaldehyde) 

Relevant academic research and scientific papers

Synthesis of (Z)-2-(4-substitutedbenzylidene)-7-isocyano-3,6-dioxo-8- phenyl-3,6-dihydro-2H-thiazolo-[3′,2′:2,3][1,2,4] triazolo[1,5-a]pyridine-9-carbonitrile

A series of (Z)-2-(4-substitutedbenzylidene)-7-isocyano-3,6-dioxo-8-phenyl- 3,6-dihydro-2H-thiazolo-[3′,2′:2,3][1,2,4]triazolo[1,5-a] pyridine-9-carbonitrile derivatives (4a-j) were obtained by the initial reaction of 5-oxo-7-phenyl-2-thiol-3,5-dihydro[1,2,4]-triazolo[1,5-a]pyridine-6,8- dicarbonitrile (3) with chloroacetic acid and appropriate aromatic aldehydes followed by fused sodium acetate condensation. The structures of the newly synthesized compounds were confirmed by IR,1H NMR, Mass and analytical data. Compounds 4a, 4f, 4i and 4j exhibited good antimicrobial activity.