131699-71-3Relevant academic research and scientific papers
RESEARCHES ON ANTIVIRAL AGENTS. 2. ENANTIOSPECIFIC SYNTHESIS OF 1,3-DIMETHYL-6-OXIRANYLPYRIMIDIN-2,4-DIONE WITH ANTI-ASFV ACTIVITY.
Botta, Maurizio,Saladino, Raffaele,Gambacorta, Augusto,Nicoletti, Rosario
, p. 441 - 444 (1990)
Chiral epoxide (+)2 has been synthetized in very good yield and high enantiomeric excess via a modified Solladie procedure starting from commercially available orotic acid.Chiral HPLC chromatographic analysis and 300 MHz 1H-NMR with the addition of chiral shift reagent Eu(hfc)3 of compound (+)2 are also reported.
