13175-78-5

Basic information

• Product Name: 2-bromo-2'-((hydroxyl)phenylmethyl)biphenyl
• CAS NO: 13175-78-5
• Molecular Weight: 339.231
• Mol File: 13175-78-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-bromo-2'-((hydroxyl)phenylmethyl)biphenyl(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-2'-((hydroxyl)phenylmethyl)biphenyl(13175-78-5)
• EPA Substance Registry System: 2-bromo-2'-((hydroxyl)phenylmethyl)biphenyl(13175-78-5)

Safety Data

• Hazardous Substances Data: 13175-78-5(Hazardous Substances Data)

Upstream product

• 13029-09-9 2,2'-dibromobiphenyl 
• 100-52-7 benzaldehyde 

Downstream Products

• 13175-79-6 2-Brom-2'-(α-brombenzyl)-biphenyl 
• 13175-80-9 2-Brom-2'-(α-methoxybenzyl)-biphenyl 

Relevant articles and documents

Synthesis of unsymmetrically substituted biaryls via sequential lithiation of dibromobiaryls using integrated microflow systems

A microflow system consisting of micromixers and microtube reactors provides an effective method for the introduction of two electrophiles onto dibromobiaryls. Selective monolithiation of dibromobiaryls, such as 2,2'-dibromobiphenyl, 4,4'-dibromobiphenyl, 2,7-dibromo-9,9-dioctylfluorene, 2,2'-dibromo-1,1'-binaphthyl, and 2,2'-dibromobibenzyl with 1 equiv of n-butyllithium followed by the reaction with electrophiles was achieved using a microflow system by virtue of fast micromixing and precise temperature control. Sequential introduction of two different electrophiles was achieved using an integrated microflow system composed of four micromixers and four microtube reactors to obtain unsymmetrically substituted biaryl compounds.