131775-99-0 Usage
Uses
Decarboxy Enrofloxacin is used as an impurity in the pharmaceutical industry for the production and quality control of Enrofloxacin (E557800). The presence of this impurity is crucial for ensuring the purity and efficacy of the final Enrofloxacin product, which is an important antibiotic used in veterinary medicine.
Used in Pharmaceutical Industry:
Decarboxy Enrofloxacin is used as an impurity for [ensuring the purity and quality control] of Enrofloxacin (E557800), an essential antibiotic in veterinary medicine. Its role in the production process helps maintain the effectiveness and safety of the final product.
Check Digit Verification of cas no
The CAS Registry Mumber 131775-99-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,1,7,7 and 5 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 131775-99:
(8*1)+(7*3)+(6*1)+(5*7)+(4*7)+(3*5)+(2*9)+(1*9)=140
140 % 10 = 0
So 131775-99-0 is a valid CAS Registry Number.
131775-99-0Relevant articles and documents
Preparation and antibacterial evaluation of decarboxylated fluoroquinolones
Nguyen, Son T.,Ding, Xiaoyuan,Butler, Michelle M.,Tashjian, Tommy F.,Peet, Norton P.,Bowlin, Terry L.
, p. 5961 - 5963 (2011)
Decarboxylated ciprofloxacin (3) has been reported in the literature to have antibacterial activities against Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis, Bacillus subtilis, Enterobacter cloacae, Serratia marcescens and especially potent activity against Escherichia coli. Herein, we report our syntheses of 3 and five additional decarboxylated fluoroquinolones (FQs). We have re-evaluated the antibacterial activity of these FQs. In contrast to previously reported data, none of these decarboxylated fluoroquinolones showed significant antibacterial activity in our assays using both the broth dilution and agar methods. Our study confirmed that the presence of a carboxylic acid group at the 3-position of the fluoroquinolone scaffold is essential for antibacterial activity.
