131792-46-6

Basic information

• Product Name: 1-<4-(benzyloxy)-5-methoxy-2-nitrobenzal>-2-methyl-1,2,3,4-tetrahydroisoquinoline
• Synonyms: 1-<4-(benzyloxy)-5-methoxy-2-nitrobenzal>-2-methyl-1,2,3,4-tetrahydroisoquinoline
• CAS NO: 131792-46-6
• Molecular Weight: 416.477
• Mol File: 131792-46-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-<4-(benzyloxy)-5-methoxy-2-nitrobenzal>-2-methyl-1,2,3,4-tetrahydroisoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 1-<4-(benzyloxy)-5-methoxy-2-nitrobenzal>-2-methyl-1,2,3,4-tetrahydroisoquinoline(131792-46-6)
• EPA Substance Registry System: 1-<4-(benzyloxy)-5-methoxy-2-nitrobenzal>-2-methyl-1,2,3,4-tetrahydroisoquinoline(131792-46-6)

Safety Data

• Hazardous Substances Data: 131792-46-6(Hazardous Substances Data)

Upstream product

• 121086-26-8 1-benzyloxy-2-methoxy-4-methyl-5-nitrobenzene 
• 3947-77-1 2-methylisoquinolinium iodide 
• 93-51-6 2-Methoxy-4-methylphenol 
• 100-44-7 benzyl chloride 

Downstream Products

• 131792-48-8 (RS)-10-(benzyloxy)-9-methoxyaporphine hydrochloride 
• 131792-47-7 (RS)-1-<2-amino-4-(benzyloxy)-5-methoxybenzyl>-2-methyl-1,2,3,4-tetrahydroisoquinoline dihydrochloride 

Relevant articles and documents

Isomeric Monomethyl Ether Derivatives of (RS)-9,10-Dihydroxyaporphine ("Isoapomorphine") as Possible Products of Metabolism by Catechol-O-methyltransferase

The isomeric monomethyl ether derivatives of (RS)-9,10-dihydroxyaporphine ("isoapomorphine") were synthesized unequivocally as possible metabolites in catechol-O-methyltransferase (COMT) mediated O-methylation reactions.In vitro incubation studies revealed that isoapomorphine is not a substrate for the COMT using experimental conditions under which apomorphine (10,11-dihydroxyaporphine) is converted in high yield into its 10-methyl ether, apocodeine.The in vivo dopaminergic inactivity of isoapomorphine (as compared with that of apomorphine) seems to be due to factors other than metabolic inactivation by COMT.