3947-77-1

Basic information

• Product Name: 2-Methylisoquinoliniumiodide
• Synonyms: 2-Methylisoquinoline-2-ium·iodide;2-methylisoquinolin-2-ium:iodide
• CAS NO: 3947-77-1
• Molecular Formula: C₁₀H₁₀N*I
• Molecular Weight: 271.10
• Mol File: 3947-77-1.mol
• Article Data: 20

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Methylisoquinoliniumiodide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methylisoquinoliniumiodide(3947-77-1)
• EPA Substance Registry System: 2-Methylisoquinoliniumiodide(3947-77-1)

Safety Data

• Hazardous Substances Data: 3947-77-1(Hazardous Substances Data)

Usage

General Description

2-Methylisoquinolinium iodide is a chemical compound with the molecular formula C11H12IN. It is a quaternary ammonium iodide salt that is often used as a reagent in organic synthesis reactions. 2-Methylisoquinolinium iodide is known for its ability to act as a catalyst in various transformation and coupling reactions, particularly in the synthesis of natural products and pharmaceuticals. Due to its strong nucleophilic nature, it is commonly used in the synthesis of functionalized molecules and has been found to be an effective catalyst in a range of organic reactions, making it an important compound in the field of organic chemistry.

InChI:InChI=1/C10H10N/c1-11-7-6-9-4-2-3-5-10(9)8-11/h2-8H,1H3/q+1

Upstream product

• 119-65-3 isoquinoline 
• 74-88-4 methyl iodide 
• 1126-71-2 N,N-dimethylphenethylamine 
• 103-83-3 N,N'-dimethylbenzylamine 
• 1637-45-2 2,2-dimethyl-1,2,3,4-tetrahydroisoquinolinium iodide 
• 14761-82-1 2-(2-dimethylaminomethylphenyl)ethanol 
• 14761-78-5 2-<2-Dimethylamino-aethyl>-benzylalkohol 

Downstream Products

• 16620-95-4 1-(4,5-dimethoxy-2-nitro-benzyl)-2-methyl-1,2-dihydro-isoquinoline 
• 14990-40-0 N-methyl-1,2,3,4-tetrahydroisoquinoline 
• 1612-65-3 2-methyl-1,2,3,4-tetrahydroisoquinoline 
• 119-65-3 isoquinoline 
• 4594-71-2 N-methylisocarbostyril 
• 491-34-9 N-methyl-1,2,3,4-tetrahydroquinoline 
• 1227952-39-7 C₁₈H₂₁NO₂ 
• 54931-61-2 4-iodo-2-methylisoquinolin-1(2H)-one 
• 1159-86-0 o-dibenzoylbenzene 

Relevant articles and documents

Metal-free reduction of unsaturated carbonyls, quinones, and pyridinium salts with tetrahydroxydiboron/water

A series of unsaturated carbonyls, quinones, and pyridinium salts have been effectively reduced to the corresponding saturated carbonyls, dihydroxybenzenes, and hydropyridines in moderate to high yields with tetrahydroxydiboron/water as a mild, convenient, and metal-free reduction system. Deuterium-labeling experiments have revealed this protocol to be an exclusive transfer hydrogenation process from water. This journal is

Regioselective Direct C-H Trifluoromethylation of Pyridine

A highly efficient and regioselective direct C-H trifluoromethylation of pyridine based on an N-methylpyridine quaternary ammonium activation strategy has been developed. A variety of trifluoromethylpyridines can be obtained in good yield and excellent re

Synthesis of 4-Iodoisoquinolin-1(2 H)-ones by a Dirhodium(II)-Catalyzed 1,4-Bisfunctionalization of Isoquinolinium Iodide Salts

An efficient Rh2(II,II)-catalyzed reaction has been developed under mild conditions. This synthetic method proceeds through iodination/oxidation of readily available isoquinolinium iodide salts under aerobic conditions with good to excellent yields. 4-Iodoisoquinolin-1(2H)-ones are important building blocks for biologically and medicinally important compounds. The developed methodology was applied to the gram-scale synthesis of a key intermediate in the synthesis of the CRTH2 antagonist CRA-680.