13182-58-6Relevant academic research and scientific papers
Solvent-free synthesis of thio-alkylxanthines from alkylxanthines using microwave irradiation
Rico-Gomez, Rodrigo,Najera, Francisco,Lopez-Romero, Juan Manuel,Ca, Pedro
, p. 2275 - 2278 (2000)
An expeditious, solvent-free procedure for the conversion of the xanthine bases theophylline, 8-methyltheophylline, caffeine, and theobromine to the corresponding 6-thio and 2,6-dithio derivatives using Lawesson's reagent under microwave irradiation is proposed.
Antioxidant properties of thio-caffeine derivatives: Identification of the newly synthesized 8-[(pyrrolidin-1-ylcarbonothioyl)sulfanyl]caffeine as antioxidant and highly potent cytoprotective agent
Jasiewicz, Beata,Sierakowska, Arleta,Wandyszewska, Natalia,War?ajtis, Beata,Rychlewska, Urszula,Wawrzyniak, Rafa?,Mrówczyńska, Lucyna
supporting information, p. 3994 - 3998 (2016/08/01)
A series of nine thio-caffeine analogues were synthesized and characterised by NMR, FT-IR and MS spectroscopic methods. Molecular structures of four of them were determined using single crystal X-ray diffraction methods. The antioxidant properties of all
Sulfidation of Selected Carboxylic and Carbonic Acid Amides with the (9-BBN)2S-Reagent
Koester, Roland,Kucznierz, Ralf
, p. 1081 - 1086 (2007/10/02)
The sulfidation of eight carboxylic and carbonic acid amides (A-H) with bis(1,5-cyclooctanediylboryl) sulfide (1) is described.From the aliphatic acyclic amide A and the N-substituted lactams C-E the corresponding thiocarbonyl compounds 2a and 2c-e, resp.
A Rapid and Efficient Synthesis of Sulfur Analogues of Pyrimidine Bases
Lapucha, Andrzej R.
, p. 256 - 258 (2007/10/02)
An improved procedure for thionation of some natural pyrimidine bases with tetraphosphorus decasulfide/sodium hydrogen carbonate is reported.Some substituted uracils and 2-thiouracils were converted into a series of analogues in which the oxygen at position 4 was replaced by sulfur atom.The advantage of this method of thionation over the older procedures is based on the tetraphosphorus decasulfide/sodium hydrogen carbonate mixture giving rise to excellent yields and simplified isolation of the desired pure products.
