1318251-52-3Relevant academic research and scientific papers
An Iron(II) Chloride-Promoted Radical Cascade Methylation or α-Chloro-β-methylation of N-Arylacrylamides with Dimethyl Sulfoxide
Li, Zejiang,Cui, Xiaosong,Niu, Lin,Ren, Yingming,Bian, Menghua,Yang, Xuebiao,Yang, Biao,Yan, Qinqin,Zhao, Jincan
, p. 246 - 249 (2017)
A free radical-initiated methylation and/or α-chloro-β-methylation of N-arylacrylamides with dimethyl sulfoxide under the analogous Fenton reaction condition has been developed, which provides an effective and facile cascade strategy for the synthesis of oxindoles and chlorinated amides. (Figure presented.).
A Free Radical Cascade Silylarylation of Activated Alkenes: Highly Selective Activation of the Si-H/C-H Bonds
Zhang, Lizhi,Liu, Dong,Liu, Zhong-Quan
, p. 2534 - 2537 (2015/06/02)
The first example of silylarylation of activated alkenes with silanes is reported via selective activation of the Si-H/C-H bonds, which allows efficient access to silylated oxindoles through a free-radical cascade process. (Chemical Equation Presented).
A convenient enantioselective synthesis of 3-asymmetrically substituted oxindoles as progesterone receptor antagonists
Alluri,Feng,Livings,Samp,Biswas,Lam,Lobkovsky,Ganguly
, p. 3945 - 3948 (2011/08/06)
A convenient enantioselective synthesis of 3-asymmetrically substituted oxindoles is reported. Compound (2) prepared by radical cyclisation of (1) was used for the synthesis of racemic and enantiomerically pure 3-asymmetrically substituted oxindoles. Desu
