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2,2'-methylenebis[(4S)-4-tert-butyl-2-oxazoline], also known as MBO, is a chiral ligand in the class of oxazoline compounds, characterized by its high enantioselectivity and stability. It is a valuable tool in organic chemistry for facilitating asymmetric transformations and is particularly appreciated for its unique structure and chiral properties, which allow it to engage in a wide range of chemical reactions for the synthesis of complex molecules with high selectivity and efficiency.

131833-91-5

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131833-91-5 Usage

Uses

Used in Asymmetric Catalysis:
2,2'-methylenebis[(4S)-4-tert-butyl-2-oxazoline] is used as a chiral ligand for enhancing the enantioselectivity of various chemical reactions. Its high selectivity and stability make it a popular choice in the synthesis of complex molecules, ensuring that the desired enantiomer is produced in higher yields.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,2'-methylenebis[(4S)-4-tert-butyl-2-oxazoline] is used as a chiral auxiliary to assist in the synthesis of enantiomerically pure compounds. This is crucial for the development of drugs with specific biological activities, as the different enantiomers of a chiral drug can have different, and sometimes opposite, effects on the body.
Used in Chemical Synthesis:
2,2'-methylenebis[(4S)-4-tert-butyl-2-oxazoline] is used as a versatile building block in the synthesis of complex organic molecules. Its ability to participate in a wide range of chemical reactions makes it an indispensable tool for creating molecules with specific properties and functions, which are essential in various chemical and material applications.
Used in Research and Development:
In the field of research and development, 2,2'-methylenebis[(4S)-4-tert-butyl-2-oxazoline] is used as a key component in the exploration of new asymmetric catalytic systems and methodologies. Its unique properties allow researchers to investigate novel reaction pathways and develop more efficient and selective synthetic processes.

Check Digit Verification of cas no

The CAS Registry Mumber 131833-91-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,1,8,3 and 3 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 131833-91:
(8*1)+(7*3)+(6*1)+(5*8)+(4*3)+(3*3)+(2*9)+(1*1)=115
115 % 10 = 5
So 131833-91-5 is a valid CAS Registry Number.

131833-91-5Downstream Products

131833-91-5Relevant academic research and scientific papers

Spectroscopic studies on complexes of magnesium (II) with C2-chiral bis-oxazolines

Singh

, p. 1713 - 1717 (1997)

The configurations of chloro, ethyl and bis-complexes of magnesium with C2-chiral bis-oxazolines such as 2,2′-methylenebis[(4S)-4-iso-propyl-2-oxazoline] (MBIO). 2,2′-methylenebis[(4S)-4-tert-butyl-2-oxazoline] (MBTO) and 2,2′-methylenebis[(4S)-4-phenyl-2-oxazoline] (MBPO) have been investigated on the basis of spectroscopic studies. The IR and NMR (1H, 13C) data suggested that the bis-oxazoline ligands coordinated magnesium (II) through both the nitrogen atoms. The molecular weight determination in nitrobenzene indicated the dimeric nature of chloro and ethylmagnesium complexes whereas bis-magnesium complexes were found to be monomeric.

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