131848-97-0 Usage
Uses
Used in Respiratory Disease Treatment:
RO-31-8425 is used as a therapeutic agent for respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD). Its anti-inflammatory and bronchodilatory effects make it a potential treatment option for these conditions.
Used in Depression Treatment:
RO-31-8425 is used as a potential antidepressant, as its effects on cAMP levels may contribute to the modulation of mood and emotional regulation.
Used in Psoriasis Treatment:
RO-31-8425 is used as a treatment for psoriasis, a chronic skin condition, due to its anti-inflammatory properties that can help reduce inflammation and skin symptoms associated with the disease.
Used in Neurodegenerative Disease Treatment:
RO-31-8425 is used as a potential treatment for neurodegenerative diseases, as its effects on cAMP levels may have neuroprotective properties and contribute to the preservation of neuronal function.
Check Digit Verification of cas no
The CAS Registry Mumber 131848-97-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,1,8,4 and 8 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 131848-97:
(8*1)+(7*3)+(6*1)+(5*8)+(4*4)+(3*8)+(2*9)+(1*7)=140
140 % 10 = 0
So 131848-97-0 is a valid CAS Registry Number.
InChI:InChI=1/C26H24N4O2/c1-29-14-18(16-6-2-4-8-19(16)29)23-24(26(32)28-25(23)31)22-17-7-3-5-9-20(17)30-11-10-15(13-27)12-21(22)30/h2-9,14-15H,10-13,27H2,1H3,(H,28,31,32)
131848-97-0Relevant academic research and scientific papers
Inhibitors of protein kinase C. 3. Potent and highly selective bisindolylmaleimides by conformational restriction
Bit,Davis,Elliott,Harris,Hill,Keech,Kumar,Lawton,Maw,Nixon,Vesey,Wadsworth,Wilkinson
, p. 21 - 29 (2007/10/02)
The protein kinase inhibitor staurosporine has been used to design a series of selective bisindolylmaleimide inhibitors of protein kinase C (PKC). Guided by molecular graphics, conformational restriction of the cationic side chain has led to ATP competiti
