1318776-83-8

Basic information

• Product Name: C₁₉H₂₄ClNO
• CAS NO: 1318776-83-8
• Molecular Weight: 317.859
• Mol File: 1318776-83-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₉H₂₄ClNO(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₉H₂₄ClNO(1318776-83-8)
• EPA Substance Registry System: C₁₉H₂₄ClNO(1318776-83-8)

Safety Data

• Hazardous Substances Data: 1318776-83-8(Hazardous Substances Data)

Upstream product

• 109-04-6 2-bromo-pyridine 
• 766-84-7 3-chloro-benzonitrile 
• 73742-07-1 (3-chlorophenyl)(pyridin-2-yl)methanone 
• 13125-66-1 n-heptylmagnesium bromide 

Relevant articles and documents

Synthesis and biological evaluation of a fluorescent analog of phenytoin as a potential inhibitor of neuropathic pain and imaging agent

Here we report on a novel fluorescent analog of phenytoin as a potential inhibitor of neuropathic pain with potential use as an imaging agent. Compound 2 incorporated a heptyl side chain and dansyl moiety onto the parent compound phenytoin and produced greater displacement of BTX from sodium channels and greater functional blockade with greatly reduced toxicity. Compound 2 reduced mechano-allodynia in a rat model of neuropathic pain and was visualized ex vivo in sensory neuron axons with two-photon microscopy. These results suggest a promising strategy for developing novel sodium channel inhibitors with imaging capabilities.