1318794-35-2

Upstream product

• 1318794-33-0 (5-bromo-2-chlorophenyl)(4-ethyloxyphenyl)fluoromethane 
• 1280647-32-6 (5-bromo-2-chlorophenyl)(4-ethyloxyphenyl)methanol 
• 461432-22-4 (5-bromo-2-chlorophenyl)(4-ethyloxyphenyl)methanone 
• 21900-52-7 5-bromo-2-chloro-benzoyl chloride 
• 21739-92-4 5-bromo-2-chlorobenzoic acid 
• 1318794-34-1 methyl 1-{4-chloro-3-[(4-ethyloxyphenyl)fluoromethyl]phenyl}-α/β-D-glucopyranoside 

Downstream Products

• 1318793-40-6 1-{4-chloro-3-[(4-ethyloxyphenyl)fluoromethyl]phenyl}-1-deoxy-β-D-glucopyranose 
• 1318794-37-4 2,3,4,6-tetra-O-acetyl-1-{4-chloro-3-[(4-ethyloxyphenyl)fluoromethyl]phenyl}-1-deoxy-β-D-glucopyranose 

Relevant academic research and scientific papers

PHENYL C-GLUCOSIDE DERIVATIVES, PREPARATION METHODS AND USES THEREOF

The present invention relates to a sodium glucose cotransporter 2 (SGLT2) inhibitor with a phenyl C-glucoside structure, its preparation method, a pharmaceutical composition containing the same, and its use in treating diabetes and preparing an anti-diabetes medicament. The invention provides a compound with the structure of general formula I and a pharmaceutically acceptable salt and prodrug ester thereof, wherein, the definitions of R5 and R6 are selected from the following: (1) R5 = R6 = Me; (2) R5 =Me, R6 = OMe; (3) R5 =Me, R6 = H; (4) R5 =Me, R6 = F; (5) R5 = F, R6 = H; and (6) R5 = OMe, R6 = H.