1318800-67-7

Basic information

• Product Name: C₂₀H₂₂Cl₂N₄O₂S
• CAS NO: 1318800-67-7
• Molecular Weight: 453.392
• Mol File: 1318800-67-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₀H₂₂Cl₂N₄O₂S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₀H₂₂Cl₂N₄O₂S(1318800-67-7)
• EPA Substance Registry System: C₂₀H₂₂Cl₂N₄O₂S(1318800-67-7)

Safety Data

• Hazardous Substances Data: 1318800-67-7(Hazardous Substances Data)

Upstream product

• 131747-55-2 2-fluoro-3-(hydroxymethyl)pyridine 
• 1318800-53-1 C₁₂H₂₃N₃OSi 
• 1318800-66-6 C₁₄H₁₉N₃O 
• 1318800-61-1 C₂₀H₃₃N₃OSi 
• 1318800-56-4 C₂₀H₃₅N₃O₂Si 
• 1339959-60-2 C₁₂H₂₀FNOSi 

Relevant articles and documents

Generation of 3,8-substituted 1,2,4-triazolopyridines as potent inhibitors of human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1)

A series of pyridyl amide/sulfonamide inhibitors of 11β-HSD-1 were modified to incorporate a novel 1,2,4-triazolopyridine scaffold. Optimization of substituents at the 3 and 8 position of the TZP core, with a special focus on enhancing metabolic stability, resulted in the identification of compound 38 as a potent and metabolically stable inhibitor of the enzyme.