1318800-81-5

Basic information

• Product Name: C₂₂H₂₆ClN₃O₃
• CAS NO: 1318800-81-5
• Molecular Weight: 415.92
• Mol File: 1318800-81-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₂H₂₆ClN₃O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₂₆ClN₃O₃(1318800-81-5)
• EPA Substance Registry System: C₂₂H₂₆ClN₃O₃(1318800-81-5)

Safety Data

• Hazardous Substances Data: 1318800-81-5(Hazardous Substances Data)

Upstream product

• 313545-20-9 (3-chloro-2-methylphenyl)boronic acid 
• 1339959-08-8 C₁₂H₉ClFNO 
• 1318800-55-3 C₁₂H₁₂ClN₃O 
• 773-34-2 4-methoxybicyclo<2.2.2>octane-1-carboxylic acid 
• 174669-74-0 2-fluoro-3-hydroxypyridine 

Downstream Products

• 1318800-98-4 C₂₁H₂₃ClN₄O 
• 1027432-42-3 C₂₂H₂₄ClN₃O₂ 
• 1318801-00-1 C₂₁H₂₁ClFN₃O 
• 1027026-71-6 C₂₁H₂₂ClN₃O₂ 

Relevant articles and documents

Generation of 3,8-substituted 1,2,4-triazolopyridines as potent inhibitors of human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1)

A series of pyridyl amide/sulfonamide inhibitors of 11β-HSD-1 were modified to incorporate a novel 1,2,4-triazolopyridine scaffold. Optimization of substituents at the 3 and 8 position of the TZP core, with a special focus on enhancing metabolic stability, resulted in the identification of compound 38 as a potent and metabolically stable inhibitor of the enzyme.