1318801-75-0Relevant academic research and scientific papers
Conjugate addition-initiated Nazarov cyclization
Brooks, Joshua L.,Caruana, Patrick A.,Frontier, Alison J.
, p. 12454 - 12457 (2011/10/09)
A reaction sequence involving the 1,6-conjugate addition of a nucleophile to a dienyl diketone followed by Nazarov cyclization is described. Several nucleophiles are identified as competent initiators for the sequence. A different reaction outcome is observed when catalytic amounts of nucleophile are employed, involving elimination of the nucleophile after the electrocyclization.
