131922-34-4

Upstream product

• 24578-12-9 Methyl 3,4-anhydro-α-D-galactopyranoside 
• 140148-02-3 (1S,2R,9R,10S)-9-azido-4,4,12,12-tetramethyl-3,5,11,13-tetraoxatricyclo<8.3.0.0^2,7>tridec-7-ene 
• 132016-22-9 (1S,2R,9S,10S)-9-amino-4,4,12,12-tetramethyl-3,5,11,13-tetraoxatricyclo[8.3.0.0^2,7]tridec-7-ene 
• 131922-33-3 methyl 4-deoxy-4-<(1R)-(1,5/4,6)-4,5,6-trihydroxy-3-hydroxymethyl-2-cyclohexenyl>amino-α-D-glucopyranoside 4',7':5',6'-di-O-isopropylidene derivative 
• 98-59-9 p-toluenesulfonyl chloride 
• 90025-02-8 (1S,2S,3S,4R)-1-amino-5-(hydroxymethyl)-2,3:4,6-di-O-isopropylidene-5-cyclohexene-2,3,4-triol 
• 131922-33-3 4',7':5',6'-Di-O-isopropylidene derivative of methyl 4-deoxy-4-<(1S)-(1,4,6/5)-4,5,6-trihydroxy-3-hydroxymethyl-2-cyclohexenyl>amino-α-D-glucopyranoside 

Downstream Products

• 140148-00-1 methyl 1'-epiacarviosin 
• 80943-41-5 methyl 4-<<(1S,2S)-(2,4/3)-2,3,4-tetrahydroxy-5-(hydroxymethyl)-5-cyclohexen-1-yl>amino>-4,6-dideoxy-α-D-glucopyranoside 
• 139964-55-9 methyl 4-deoxy-4-<(1R)-(1,5/4,6)-4,5,6-trihydroxy-3-hydroxymethyl-2-cyclohexenyl>amino-6-O-p-tolylsulfonyl-α-D-glucopyranoside 2,3:4',7':5',6'-tri-O-isopropylidene derivative 

Relevant academic research and scientific papers

Alternative synthesis and enzyme-inhibitory activity of methyl 1'-epiacarviosin and its 6-hydroxy analog

Methyl 1′-epiacarviosin and its 6-hydroxy analog were synthesized. The inhibitory activities of these compounds against enzymes are covered. The enzymes covered include glucosidase and mannosidase. The details of the syntheses are presented.

Chemical modification of the sugar part of methyl acarviosin: Synthesis and inhibitory activities of nine analogues

Nine analogues of methyl acarviosin (1), the core structure of acarbose and its homologues, the 6-hydroxy-(2), 6-azido-(3), 6-amino-(4), 6-acctamido-(5), 6-methoxy-(6), 6-hydroxy-2-O-methyl-(8), and 6-hydroxy-3-O-methyl derivatives (9), including the 5-me