80943-41-5

Upstream product

• 38231-86-6 valienamine 
• 89859-43-8 methyl 2,3-O-cyclohexylidene-6-deoxy-α-D-xylo-hexopyranosid-4-ulose 
• 56180-94-0 acarbose 
• 131922-33-3 4',7':5',6'-Di-O-isopropylidene derivative of methyl 4-deoxy-4-<(1S)-(1,4,6/5)-4,5,6-trihydroxy-3-hydroxymethyl-2-cyclohexenyl>amino-α-D-glucopyranoside 
• 131922-34-4 4',7':5',6'-Di-O-isopropylidene derivative of methyl 4-deoxy-6-O-p-tolylsulfonyl-4-<(1S)-(1,4,6/5)-4,5,6-trihydroxy-3-hydroxymethyl-2-cyclohexenyl>amino-α-D-glucopyranoside 
• 90025-02-8 (1S,2S,3S,4R)-1-amino-5-(hydroxymethyl)-2,3:4,6-di-O-isopropylidene-5-cyclohexene-2,3,4-triol 
• 24578-12-9 Methyl 3,4-anhydro-α-D-galactopyranoside 
• 142200-26-8 Methyl-4-<(1S)-(1,4,6/5)-4,5,6-trihydroxy-3-hydroxymethyl-2-cyclohexen-1-yl>amino-D-glucopyranosid 

Relevant academic research and scientific papers

Synthesis and study of the pancreatic α-amylase inhibitory activity of methyl acarviosin and its derivatives

Pancreatic α-amylase is a target for type 2 diabetes mellitus treatment. However, small molecule inhibitors of α-amylase are currently scarce. In the course of developing small molecule α-amylase inhibitors, we designed and synthesized conjugates of gluco

Chemical modification of the sugar part of methyl acarviosin: Synthesis and inhibitory activities of nine analogues

Nine analogues of methyl acarviosin (1), the core structure of acarbose and its homologues, the 6-hydroxy-(2), 6-azido-(3), 6-amino-(4), 6-acctamido-(5), 6-methoxy-(6), 6-hydroxy-2-O-methyl-(8), and 6-hydroxy-3-O-methyl derivatives (9), including the 5-me

UNTERSUCHUNGEN ZUR STRUCTUR DES α-D-GLUCOSIDASEINHIBITORS ACARBOSE

Hydrolysis of the pseudotetrasaccharide acarbose (1), a potent inhibitor of intestinal α-D-glucosidases and effective oral antidiabetic agent, gave D-glucose and a tricyclic compound (1R,2S,3R,4aS,7R,8S,8aS,9aR)-1,2,3,4a,7,8,8a,9a-octahydro-1,2,7,8-tetrah