13193-61-8Relevant academic research and scientific papers
Iridium-Catalyzed Aryl C-H Sulfonamidation and Amide Formation Using a Bifunctional Nitrogen Source
Yu, Meng,Zhang, Tao,Jalani, Hitesh B.,Dong, Xunqing,Lu, Hongjian,Li, Guigen
, p. 4828 - 4832 (2018/08/24)
A new strategy for the sequential formation of aryl and amidyl C-N bonds is reported. Using trichloroethoxysulfonyl azide as a bifunctional nitrogen source, Ir-catalyzed aryl C-H sulfonamidation and subsequent desulfonative amide formation proceed effectively without any need of oxidants or coupling reagents. This protocol is suitable for readily available benzamides and stable carboxylates including primary, secondary, and tertiary alkyl, alkenyl, and phenyl carboxylates, thereby providing a direct and efficient method for the synthesis of biologically and chemically useful N-arylamides.
Mechanochemical Rhodium(III)-Catalyzed C-H Bond Amidation of Arenes with Dioxazolones under Solventless Conditions in a Ball Mill
Hermann, Gary N.,Bolm, Carsten
, p. 4592 - 4596 (2017/07/24)
A procedure for the direct mechanochemical rhodium(III)-catalyzed C-H bond amidation of arenes with 1,4,2-dioxazol-5-ones as the nitrogen source has been developed. The transformation proceeds under solventless conditions and does not require additional h
