131933-47-6

Basic information

• Product Name: 1-<2',3'-dideoxy-3'(R)-phenylseleno-β-D-glycero-pentofuranosyl>thymine
• Synonyms: 1-<2',3'-dideoxy-3'(R)-phenylseleno-β-D-glycero-pentofuranosyl>thymine
• CAS NO: 131933-47-6
• Molecular Weight: 381.29
• Mol File: 131933-47-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-<2',3'-dideoxy-3'(R)-phenylseleno-β-D-glycero-pentofuranosyl>thymine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-<2',3'-dideoxy-3'(R)-phenylseleno-β-D-glycero-pentofuranosyl>thymine(131933-47-6)
• EPA Substance Registry System: 1-<2',3'-dideoxy-3'(R)-phenylseleno-β-D-glycero-pentofuranosyl>thymine(131933-47-6)

Safety Data

• Hazardous Substances Data: 131933-47-6(Hazardous Substances Data)

Upstream product

• 42214-24-4 1-(2-deoxy-3-O-methanesulfonyl-5-O-trityl-β-D-ribopentofuranosyl)thymine 
• 111647-36-0 5'-O-(4,4'-dimethoxytrityl)-3'-mesyl-2',3'-dideoxythymidine 
• 1370642-71-9 C₃₇H₃₆N₂O₆Se 
• 130446-05-8 1-{(2R,4R,5R)-5-[(4-Methoxy-phenyl)-diphenyl-methoxymethyl]-4-phenylselanyl-tetrahydro-furan-2-yl}-5-methyl-1H-pyrimidine-2,4-dione 
• 131933-46-5 3'-β-(phenylselenyl)-5'-O-trityl-3'-deoxythymidine 
• 65-71-4 thymin 
• 124680-51-9 (2R,4R,5R)-1-[5-[bis(4-methoxyphenyl)phenylmethoxymethyl]-4-hydroxytetrahydrofuran-2-yl]-5-methyl-1H-pyrimidine-2,4-dione 
• 1666-13-3 diphenyl diselenide 

Downstream Products

• 3416-05-5 3'-Deoxythymidine 
• 1419743-24-0 3'-β-(selenophenyl)-2',3'-dideoxythymidine-5'-yl H-phosphonate triethylammonium salt 
• 138904-52-6 1-<5'-O-(2-propynyl)-2',3'-dideoxy-3'(R)-phenylseleno-β-D-glycero-pentofuranosyl>thymine 
• 138904-49-1 1-<5'-O-allyl-2',3'-dideoxy-3'(R)-phenylseleno-β-D-glycero-pentofuranosyl>thymine 
• 3056-17-5 stavudin 
• 138904-55-9 1-<5'-O-(1-oxo-hex-2-ene-1yl)-2',3'-dideoxy-3'(R)-phenylseleno-β-D-glycero-pentofuranosyl>thymine 
• 138904-53-7 1-<5'-O-(1-oxo-prop-2-ene-1yl)-2',3'-dideoxy-3'(R)-phenylseleno-β-D-glycero-pentofuranosyl>thymine 
• 138904-54-8 1-<5'-O-(1-oxo-but-2-ene-1yl)-2',3'-dideoxy-3'(R)-phenylseleno-β-D-glycero-pentofuranosyl>thymine 
• 138904-50-4 1-<5'-O-(3-methyl-2-butenyl)-2',3'-dideoxy-3'(R)-phenylseleno-β-D-glycero-pentofuranosyl>thymine 

Relevant articles and documents

Synthesis of C3′ modified nucleosides for selective generation of the C3′-deoxy-3′-thymidinyl radical: A proposed intermediate in LEE induced DNA damage

DNA damage pathways induced by low-energy electrons (LEEs) are believed to involve the formation of 2-deoxyribose radicals. These radicals, formed at the C3′ and C5′ positions of nucleotides, are the result of cleavage of the C-O phosphodiester bond throu

Synthesis of Furo[2,3-c]pyran-β-D-nucleosides by radical-cyclization and their conformational analysis by 500 MHz 1H-NMR spectroscopy

Free-radical, generated from the 3'-phenylseleno nucleosides as the radical precursors 2-5, was efficiently trapped intramolecularly by an olefin or alkyne function anchored from the 5'-end by an ether function to give various [3.4.0]-cis-fused furo[2,3-c