131968-87-1

Upstream product

• 19810-31-2 Benzyloxyacetyl chloride 
• 24978-42-5 1,4-bis(4'-methoxyphenyl)-1,4-diazabuta-1,3-diene 
• 153545-44-9 (1S,2S,3'R,4'S,3''S,4''R)-1,2-Bis<1'-(p-methoxyphenyl)-3'-(benzyloxy)-2'-oxo-azetidin-4'-yl>ethane-1,2-diol 
• 24978-42-5 (E,E)-N¹,N²-bis(4-methoxyphenyl)ethane-1,2-diimine 
• 153545-43-8 (4S,5S,3'R,4'S,3''S,4''R)-2,2-Dimethyl-4,5-bis<1'-(p-methoxyphenyl)-3'-(benzyloxy)-2'-oxo-azetidin-4'-yl>-1,3-dioxolane 
• 88315-63-3 (E)-4-methoxy-N-((E)-3-phenylallylidene)aniline 
• 104-94-9 4-methoxy-aniline 
• 153472-20-9 C₂₁H₂₄N₂O₄ 
• 130422-40-1 cis-1-p-methoxyphenyl-3-benzyloxy-4-styrylazetidin-2-one 

Downstream Products

• 136137-16-1 (3S,4R)-3-Benzyloxy-1-(4-methoxy-phenyl)-4-{[(E)-4-methoxy-phenylimino]-methyl}-azetidin-2-one 
• 136137-19-4 1-p-methoxyphenyl-3-benzyloxy-4-(1'-p-methoxyphenyl-3'-phenoxyazetidin-2'-one-4'-yl)-azetidin-2-one 
• 184423-99-2 3-Benzyloxy-1-(4-methoxy-phenyl)-azetidin-2-one 
• 184423-94-7 2-Benzyloxy-3-hydroxy-N-(4-methoxy-phenyl)-propionamide 

Relevant academic research and scientific papers

Synthesis of novel 4-(5'-pyrrolidinyl)-β-lactams

The synthesis of novel 4-(5'-pyrrolidinyl)-β-lactams from imines derived from 4-formyl-β-lactams and α-amino esters via cascade imine → azomethine ylide → 1,3-dipolar cycloaddition reactions is described. These cascades are endo-specific, exhibit facial stereoselectivity and occur in good to excellent yields.

Diastereoselective synthesis of bis-beta-lactams

Schiff bases derived from (±)-4-aldehydo-2- -azetidinones react with acid chlorides and triethylamine to produce (±)-bis-β-lactams in a diastereoselective fashion. The steric course of β-lactam fonnation was determined in one case by using chiral HPLC sep