88315-63-3

Basic information

• Product Name: (E)-4-methoxy-N-((E)-3-phenylallylidene)aniline
• Synonyms: (E)-4-methoxy-N-((E)-3-phenylallylidene)aniline
• CAS NO: 88315-63-3
• Molecular Weight: 237.301
• Mol File: 88315-63-3.mol
• Article Data: 39

Chemical Properties

• CAS DataBase Reference: (E)-4-methoxy-N-((E)-3-phenylallylidene)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-4-methoxy-N-((E)-3-phenylallylidene)aniline(88315-63-3)
• EPA Substance Registry System: (E)-4-methoxy-N-((E)-3-phenylallylidene)aniline(88315-63-3)

Safety Data

• Hazardous Substances Data: 88315-63-3(Hazardous Substances Data)

Usage

General Description

(E)-4-methoxy-N-((E)-3-phenylallylidene)aniline, also known as Vanillin Aniline, is a chemical compound consisting of a methoxy group, an allylidene group, and an aniline group. It is commonly used in the synthesis of various organic compounds and pharmaceuticals. (E)-4-methoxy-N-((E)-3-phenylallylidene)aniline has a wide range of applications, including being used as a fragrance in perfumes and as a flavoring agent in food and beverages. Additionally, it also has potential uses in the pharmaceutical industry for the development of new drugs. However, caution should be exercised when handling this chemical due to its potential hazards and harmful effects if not used properly.

Upstream product

• 104-94-9 4-methoxy-aniline 
• 104-55-2 3-phenyl-propenal 
• 2101-87-3 p-methoxy-phenylazide 
• 14371-10-9 (E)-3-phenylpropenal 
• 100-17-4 para-methoxynitrobenzene 
• 104-54-1 3-Phenylpropenol 
• 98-80-6 phenylboronic acid 
• 100-52-7 benzaldehyde 
• 22774-93-2 N-cinnamyl-4-methoxybenzenamine 

Downstream Products

• 4789-73-5 2-phenyl-6-methoxyquinoline 
• 93202-14-3 2-(4-methoxyphenyliminomethyl)-3-phenylquinoxaline 1,4-dioxide 
• 103733-13-7 3-ethyl-1-(4-methoxyphenyl)-4-styrylazetidin-2-one 
• 84209-24-5 cis-1-p-methoxyphenyl-3-phthalimido-4-styrylazetidin-2-one 
• 84423-24-5 4a-Methoxy-7-(4-methoxy-3,6-dioxo-cyclohexa-1,4-dienyl)-1-(4-methoxy-phenyl)-4-phenyl-1,4,4a,8a-tetrahydro-quinoline-5,8-dione 
• 84423-29-0 4a,4'a-Dimethoxy-1,1'-bis-(4-methoxy-phenyl)-4,4'-diphenyl-1,4,4a,8a,1',4',4'a,8'a-octahydro-[7,7']biquinolinyl-5,8,5',8'-tetraone 
• 138215-28-8 (3R,4S)-3-Fluoro-1-(4-methoxy-phenyl)-3-phenyl-4-((E)-styryl)-azetidin-2-one 
• 100009-52-7 (3S,4R)-3-((S)-1-Hydroxy-ethyl)-1-(4-methoxy-phenyl)-4-((E)-styryl)-azetidin-2-one 
• 101977-77-9 <3S,4S(E)>-3-<1(S)-hydroxyethyl>-1-(4-methoxyphenyl)-4-(2-phenylethenyl)-2-azetidinone 
• 85393-36-8 4-Methoxy-N-[1-(4-methoxy-phenyl)-3-methyl-2-oxo-4-phenyl-1,2,3,4-tetrahydro-pyridin-3-yl]-benzamide 
• 132554-77-9 ((E)-1,3-Diphenyl-allyl)-(4-methoxy-phenyl)-amine 
• 93390-64-8 (4-Methoxy-phenyl)-phenyl-(2,3,3-triphenyl-propyl)-amine 
• 205525-21-9 (1'S,3S)-3-(1'-hydroxyethyl)-1-(4'-methoxyphenyl)-4-(2'-phenylethenyl)-2-azetidinone 
• 84355-68-0 1-(4-methoxyphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile 

Relevant articles and documents

A Novel ZnII Complex Bearing Two Monodentate (4-Methoxyphenyl)[(1E, 2E)-3-phenylprop-2-en-1-ilidene] Schiff Bases: Crystal Structure and DFT Study

A novel ZnII complex bearing two monodentate (4-methoxyphenyl)[(1E, 2E)-3-phenylprop-2-en-1-ilidene] Schiff bases was synthesized and investigated both in the solid state by single-crystal X-ray diffraction, elemental analysis, and FTIR and in

Iron-Catalyzed Hydrogen Transfer Reduction of Nitroarenes with Alcohols: Synthesis of Imines and Aza Heterocycles

A straightforward and selective reduction of nitroarenes with various alcohols was efficiently developed using an iron catalyst via a hydrogen transfer methodology. This protocol led specifically to imines in 30-91% yields, with a good functional group tolerance. Noticeably, starting from o-nitroaniline derivatives, in the presence of alcohols, benzimidazoles can be obtained in 64-72% yields when the reaction was performed with an additional oxidant, DDQ, and quinoxalines were prepared from 1,2-diols in 28-96% yields. This methodology, unprecedented at iron for imines, also provides a sustainable alternative for the preparation of quinoxalines and benzimidazoles.

Stereoselective Construction of γ-Lactams via Copper-Catalyzed Borylacylation

A versatile and highly stereoselective borylative cyclization to generate polyfunctionalized γ-lactams has been developed. The stereoselective synthesis of these key ring systems is crucial due to their ubiquity in natural products. We report the diastero- and enantioselective construction of di- and trisubstituted γ-lactam cores, with examples containing an enantioenriched quaternary carbon.