1320232-35-6Relevant academic research and scientific papers
Three-component coupling synthesis of diversely substituted n-aryl pyrroles catalyzed by iron(III) chloride
Sarkar, Soumen,Bera, Krishnendu,Maiti, Sukhendu,Biswas, Srijit,Jana, Umasish
supporting information, p. 1563 - 1570 (2013/05/21)
An efficient and operationally simple three-component coupling synthesis of varieties of N-aryl substituted pyrroles is described in the presence of sustainable and environmentally benign metal catalyst, FeCl3. This method provides a straightforward approach for the synthesis of N-aryl substituted pyrroles in good yields from easily accessible starting materials such as nitroalkenes, 1,3-dicarbonyl compounds, and primary aromatic amines. The reaction proceeds through a catalytic sequence of Fe(III)-catalyzed amination/ Michael/cycloisomerization reactions. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications1 to view the free supplemental file. Copyright Taylor & Francis Group, LLC.
A facile and efficient synthesis of multisubstituted pyrroles from enaminoesters and nitroolefins
Guan, Zheng-Hui,Li, Liang,Ren, Zhi-Hui,Li, Jianli,Zhao, Mi-Na
supporting information; experimental part, p. 1664 - 1668 (2011/08/10)
A facile and efficient method for the synthesis of substituted pyrroles from enaminoesters and nitroolefins is reported. This general procedure provides a wide variety of multisubstituted pyrroles in good to excellent yields under mild reaction conditions.
