132067-87-9

Basic information

• Product Name: 6,7-Dimethoxy-8bphenyl-1,1-dichloro-3,3-diethyl-1,3,4,8b-tetrahydroazirino<2,1-a>isoquinoline
• Synonyms: 6,7-Dimethoxy-8bphenyl-1,1-dichloro-3,3-diethyl-1,3,4,8b-tetrahydroazirino<2,1-a>isoquinoline
• CAS NO: 132067-87-9
• Molecular Weight: 406.352
• Mol File: 132067-87-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6,7-Dimethoxy-8bphenyl-1,1-dichloro-3,3-diethyl-1,3,4,8b-tetrahydroazirino<2,1-a>isoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 6,7-Dimethoxy-8bphenyl-1,1-dichloro-3,3-diethyl-1,3,4,8b-tetrahydroazirino<2,1-a>isoquinoline(132067-87-9)
• EPA Substance Registry System: 6,7-Dimethoxy-8bphenyl-1,1-dichloro-3,3-diethyl-1,3,4,8b-tetrahydroazirino<2,1-a>isoquinoline(132067-87-9)

Safety Data

• Hazardous Substances Data: 132067-87-9(Hazardous Substances Data)

Upstream product

• 67-66-3 chloroform 
• 132067-80-2 3,3-Diethyl-6,7-dimethoxy-1-phenyl-3,4-dihydro-isoquinoline 

Downstream Products

• 132067-88-0 1-Hydroxy-7,8-dimethoxy-4,4-diethyl-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one 

Relevant articles and documents

REACTION OF DICHLOROCARBENE WITH SUBSTITUTED 3,4-DIHYDROISOQUINOLINES AND 1-METHYLENE-1,2,3,4-TETRAHYDROISOQUINOLINES

Reaction of dichlorocarbene with 3,3-dialkyl-3,4-dihydroisoquinolines results in the formation of gem-dichloroazirinoisoquinolines, which are in turn converted to 3-benzazepinones upon hydrolysis.Reaction of dichlorocarbene with the ethyl ester or amide of (3,3-dimethyl-1,2,3,4-tetrahydroisoquinolin-1-ylidene)acetic acid is accompanied by rearrangement of the intermediate carbene adducts at the enamine C=C bond and results in the formation of a 1-azadiene, 3-(3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)-3-chloroacrylic acid ethyl ester, and a spirolactam, 3,3-dimethyl-3-chlorospiro-5'(2'H)- one, respectively.