13211-00-2

Basic information

• Product Name: N-(4-butyrylphenyl)acetamide
• Synonyms: N-(4-butyrylphenyl)acetamide
• CAS NO: 13211-00-2
• Molecular Formula: C₁₂H₁₅NO₂
• Molecular Weight: 205.253
• Mol File: 13211-00-2.mol
• Article Data: 4

Chemical Properties

• Melting Point: 142 °C(Solv: water (7732-18-5))
• Boiling Point: 406.1±28.0 °C(Predicted)
• Appearance: /
• Density: 1.097±0.06 g/cm3(Predicted)
• PKA: 14.57±0.70(Predicted)
• CAS DataBase Reference: N-(4-butyrylphenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-butyrylphenyl)acetamide(13211-00-2)
• EPA Substance Registry System: N-(4-butyrylphenyl)acetamide(13211-00-2)

Safety Data

• Hazardous Substances Data: 13211-00-2(Hazardous Substances Data)

Upstream product

• 1688-71-7 1-(4-aminophenyl)butan-1-one 
• 108-24-7 acetic anhydride 
• 102-82-9 tributyl-amine 
• 622-50-4 4-Acetamido-1-iodobenzene 
• 141-75-3 butyryl chloride 
• 103-84-4 Acetanilid 

Downstream Products

• 1094374-40-9 N-(4-(2-ethylbutanoyl)phenyl)acetamide 
• 1332615-95-8 N-(4-(2-(dimethylamino)butanoyl)phenyl)acetamide 
• 1332601-45-2 N-(4-(2-(dimethylamino)-1-hydroxybutyl)phenyl)acetamide 
• 227283-96-7 N-(4-(2-(dimethylamino)-1-(1H-imidazol-1-yl)butyl)phenyl)acetamide 
• 1351956-60-9 4-(2-(dimethylamino)-1-(1H-imidazol-1-yl)butyl)aniline 
• 1351956-89-2 N-(4-(2-ethyl-1-(1H-imidazol-1-yl)butyl)phenyl)acetamide 
• 1351956-90-5 4-(2-ethyl-1-(1H-imidazol-1-yl)butyl)aniline 
• 1351956-92-7 methyl 4-(6-(2-ethyl-1-(1H-imidazol-1-yl)butyl)benzo[d]thiazol-2-yl)benzoate 
• 1351956-93-8 4-(6-(2-ethyl-1-(1H-imidazol-1-yl)butyl)benzo[d]thiazol-2-yl)benzoic acid 
• 1310320-05-8 N-(4-(2-bromobutanoyl)phenyl)acetamide 
• 1351956-78-9 4-((6-(-2-(dimethylamino)-1-(1H-imidazol-1-yl)butyl)benzo[d]thiazol-2-yl)amino)benzoic acid 
• 1351956-77-8 methyl 4-((6-(-2-(dimethylamino)-1-(1H-imidazol-1-yl)butyl)benzo[d]thiazol-2-yl)amino)benzoate 
• 1351956-66-5 isopropyl 3-(((6-(-2-(dimethylamino)-1-(1H-imidazol-1-yl)butyl)benzo[d]thiazol-2-yl)amino)methyl)benzoate 
• 1351957-41-9 ethyl 3-(((6-(2-(dimethylamino)-1-(1H-imidazol-1-yl)butyl)benzo[d]thiazol-2-yl)amino)methyl)benzoate 

Relevant articles and documents

CYTOCHROME P450 INHIBITORS AND USES THEREOF

The present invention provides compounds having the general structural formula (I) and pharmaceutically acceptable derivatives thereof, as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases involving fibrosis and proliferation, and where anti-fibrotic or anti-proliferative activity is beneficial.

Palladium-catalyzed oxidative coupling of trialkylamines with aryl iodides leading to alkyl aryl ketones

Chemical equations presented. A new, simple method for selectively synthesizing alkyl aryl ketones has been developed by palladium-catalyzed oxidative coupling of trialkylamines with aryl iodides. In the presence of PdCl2(MeCN)2, TBAB, and ZnO, a variety of aryl iodides underwent an oxidative coupling reaction with tertiary amines and water to afford the corresponding alkyl aryl ketones in moderate to excellent yields. It is noteworthy that this method is the first example of using trialkylamines as the carbonyl sources for constructing alkyl aryl ketone skeletons.