13211-56-8 Usage
Description
1-ISOQUINOLINYL(4-METHOXYPHENYL)METHANOL is a chemical compound characterized by a molecular formula C19H17NO2. It features a 1-isoquinolinyl group linked to a 4-methoxyphenyl group, which is further connected to a methanol moiety. 1-ISOQUINOLINYL(4-METHOXYPHENYL)METHANOL holds promise in medicinal chemistry due to its potential for diverse pharmacological activities and is considered valuable in research and drug development. It may serve as a pharmaceutical intermediate or a building block for synthesizing other organic compounds.
Uses
Used in Pharmaceutical Industry:
1-ISOQUINOLINYL(4-METHOXYPHENYL)METHANOL is used as a pharmaceutical intermediate for its potential to contribute to the development of new drugs. Its unique structure and pharmacological properties make it a candidate for further exploration in medicinal chemistry.
Used in Research and Development:
In the field of research and development, 1-ISOQUINOLINYL(4-METHOXYPHENYL)METHANOL is utilized as a building block for the synthesis of other organic compounds. Its diverse biological properties and potential applications in drug discovery highlight its importance in creating novel therapeutic agents.
Used in Medicinal Chemistry:
1-ISOQUINOLINYL(4-METHOXYPHENYL)METHANOL is employed in medicinal chemistry for its potential to exhibit various pharmacological activities. Its unique structure allows for the exploration of its interactions with biological targets, which could lead to the discovery of new therapeutic agents with improved efficacy and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 13211-56-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,2,1 and 1 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 13211-56:
(7*1)+(6*3)+(5*2)+(4*1)+(3*1)+(2*5)+(1*6)=58
58 % 10 = 8
So 13211-56-8 is a valid CAS Registry Number.
13211-56-8Relevant articles and documents
Photocatalytic redox-neutral hydroxyalkylation of: N -heteroaromatics with aldehydes
Fukatsu, Arisa,Fuse, Hiromu,Kanai, Motomu,Kondo, Mio,Masaoka, Shigeyuki,Mitsunuma, Harunobu,Nakao, Hiroyasu,Saga, Yutaka
, p. 12206 - 12211 (2020/11/26)
Hydroxyalkylation of N-heteroaromatics with aldehydes was achieved using a binary hybrid catalyst system comprising an acridinium photoredox catalyst and a thiophosphoric acid organocatalyst. The reaction proceeded through the following sequence: (1) photoredox-catalyzed single-electron oxidation of a thiophosphoric acid catalyst to generate a thiyl radical, (2) cleavage of the formyl C-H bond of the aldehyde substrates by a thiyl radical acting as a hydrogen atom transfer catalyst to generate acyl radicals, (3) Minisci-type addition of the resulting acyl radicals to N-heteroaromatics, and (4) a spin-center shift, photoredox-catalyzed single-electron reduction, and protonation to produce secondary alcohol products. This metal-free hybrid catalysis proceeded under mild conditions for a wide range of substrates, including isoquinolines, quinolines, and pyridines as N-heteroaromatics, as well as both aromatic and aliphatic aldehydes, and tolerated various functional groups. The reaction was applicable to late-stage derivatization of drugs and their leads. This journal is
