1321545-25-8

Basic information

• Product Name: (S)-2-(4-benzyloxy-3-methoxybenzyl)pent-4-en-1-ol
• Synonyms: (S)-2-(4-benzyloxy-3-methoxybenzyl)pent-4-en-1-ol
• CAS NO: 1321545-25-8
• Molecular Weight: 312.409
• Mol File: 1321545-25-8.mol

Chemical Properties

• CAS DataBase Reference: (S)-2-(4-benzyloxy-3-methoxybenzyl)pent-4-en-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(4-benzyloxy-3-methoxybenzyl)pent-4-en-1-ol(1321545-25-8)
• EPA Substance Registry System: (S)-2-(4-benzyloxy-3-methoxybenzyl)pent-4-en-1-ol(1321545-25-8)

Safety Data

• Hazardous Substances Data: 1321545-25-8(Hazardous Substances Data)

Upstream product

• 116185-11-6 benzyl 3-[4-(benzyloxy)-3-methoxyphenyl]propanoate 
• 30034-49-2 β-(4-benzyloxy-3-methoxyphenyl)propionic acid 
• 1135-23-5 3-(4-hydroxy-3-methoxyphenyl)propionic acid 
• 1135-24-6 3-(4-hydroxy-3-methoxyphenyl)acrylic acid 
• 1321545-28-1 (S)-3-[3-(4-benzyloxy-3-methoxyphenyl)propanoyl]-4-isopropyloxazolidin-2-one 
• 1321545-26-9 (S)-3-[(S)-2-(4-benzyloxy-3-methoxybenzyl)pent-4-enoyl]-4-isopropyloxazolidin-2-one 

Downstream Products

• 3688-23-1 (-)-secoisolariciresinol 
• 111266-03-6 (R)-(+)-3-(4-benzyloxy-3-methoxybenzyl)-γ-butyrolactone 
• 111194-07-1 (3R,4R)-3,4-bis(4-benzyloxy-3-methoxybenzyl)dihydrofuran-2(3H)-one 
• 580-72-3 matairesinol 

Relevant articles and documents

An access to chiral β-benzyl-γ-butyrolactones and its application to the synthesis of enantiopure (+)-secoisolariciresinol, (-)-secoisolariciresinol, and (-)-enterolactone

Both enantiomers of secoisolariciresinol and enantiopure (-)-enterolactone were synthesized through a highly stereoselective convergent synthesis. An Evans diastereoselective alkylation followed by a substrate-induced diastereoselective -alkylation of the newly formed optically active β-benzyl-γ- butyrolactone gave the β-β′ linkage of the target skeleton. The (S,S)- and (R,R)-enantiomers of secoisolariciresinol and (-)-enterolactone were obtained in 12-14% (11 steps) and 20% (7 steps) overall yield, respectively. Georg Thieme Verlag Stuttgart New York.