132183-40-5

Upstream product

• 3029-19-4 pyrene-1-aldehyde 
• 132183-37-0 2'-Deoxy-N⁶-(1-pyrenylmethyl)-3',5'-di-O-p-toluoyladenosine 
• 3786-56-9 1-pyrene carboxaldehyde oxime 
• 1006061-57-9 1-(azidomethyl)pyrene 
• 3786-54-7 1-aminomethylpyrene 
• 24463-15-8 1-pyrenemethanol 
• 958-09-8 2'-deoxy-D-adenosine 
• 292862-89-6 N⁶-[(1H-benzotriazol-1-yl)(pyren-1-yl)methy]-2'-deoxyadenosine 
• 132183-36-9 (-)-N⁶-(1-pyrenylmethyl)-2'-deoxyadenosine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 

Downstream Products

• 132183-10-9 (+/-)-N⁶-(1-Pyrenylmethyl)-2'-deoxy-3'-(N,N-diisopropyl-2-cyanoethyl)-5'-(p-dimethoxytrityl)adenosine phosphoramidite 

Relevant academic research and scientific papers

1H-benzotriazole as synthetic auxiliary in a facile route to N6- (arylmethyl)-2'-deoxyadenosines: DNA intercalators inserted into three-way junctions

The 2'-deoxy-N6-(naphthalen-1-ylmethyl)- (5a) and N6-(pyren-1- ylmethyl)adenosine (5b) were synthesized in two steps from 2'-deoxyadenosine and the adequate arenecarbaldehyde with 1H-benzotriazole as a synthetic auxiliary (Scheme). W

A rapid, high-yield method for 5'-hydroxyl protection in very reactive and amino group modified nucleosides using dimethoxytrityl tetrafluoroborate

The conventional method for 4,4'-dimethoxytrityl (DMT) etherification of the 5'hydroxyl termini in deoxynucleosides that are either highly reactive or those bearing modifications at the exocyclic amino group can be quite problematic, and in several cases

Synthesis of Oligonucleotide Adducts of the Bay Region Diol Epoxide Metabolites of Carcinogenic Polycyclic Aromatic Hydrocarbons

An efficient method for the site-specific synthesis of adducts between the biologically active diol epoxide metabolites of carcinogenic polycyclic aromatic hydrocarbons (PAHs) and oligonucleotides in which a PAH component of predetermined stereochemistry

Syntheses of polycyclic aromatic hydrocarbon-nucleoside and oligonucleotide adducts specifically alkylated on the amino functions of deoxyguanosine and deoxyadenosine

Efficient syntheses of 1-pyrenylmethyl-mononucleoside adducts with the hydrocarbon moiety atached to the exocyclic amino functions of deoxyguanosine and deoxyadenosine are described.