132183-10-9

Upstream product

• 132183-37-0 2'-Deoxy-N⁶-(1-pyrenylmethyl)-3',5'-di-O-p-toluoyladenosine 
• 3786-54-7 1-aminomethylpyrene 
• 3786-56-9 1-pyrene carboxaldehyde oxime 
• 958-09-8 2'-deoxy-D-adenosine 
• 292862-89-6 N⁶-[(1H-benzotriazol-1-yl)(pyren-1-yl)methy]-2'-deoxyadenosine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 3029-19-4 pyrene-1-aldehyde 
• 124482-92-4 2-cyanoethyl-N,N-(diisopropylamino)chlorophosphine 
• 132183-40-5 2'-deoxy-5-O-(4,4'-dimethoxytrityl)-N⁶-(pyren-1-ylmethy)adenosine 

Relevant academic research and scientific papers

1H-benzotriazole as synthetic auxiliary in a facile route to N6- (arylmethyl)-2'-deoxyadenosines: DNA intercalators inserted into three-way junctions

The 2'-deoxy-N6-(naphthalen-1-ylmethyl)- (5a) and N6-(pyren-1- ylmethyl)adenosine (5b) were synthesized in two steps from 2'-deoxyadenosine and the adequate arenecarbaldehyde with 1H-benzotriazole as a synthetic auxiliary (Scheme). W

Synthesis of Oligonucleotide Adducts of the Bay Region Diol Epoxide Metabolites of Carcinogenic Polycyclic Aromatic Hydrocarbons

An efficient method for the site-specific synthesis of adducts between the biologically active diol epoxide metabolites of carcinogenic polycyclic aromatic hydrocarbons (PAHs) and oligonucleotides in which a PAH component of predetermined stereochemistry

Syntheses of polycyclic aromatic hydrocarbon-nucleoside and oligonucleotide adducts specifically alkylated on the amino functions of deoxyguanosine and deoxyadenosine

Efficient syntheses of 1-pyrenylmethyl-mononucleoside adducts with the hydrocarbon moiety atached to the exocyclic amino functions of deoxyguanosine and deoxyadenosine are described.