132195-42-7

Basic information

• Product Name: 2,6-Dichloro-5-fluoro-4-methylpyridine-3-carboxylic acid
• Synonyms: 2,6-Dichloro-5-fluoro-4-methylpyridine-3-carboxylic acid;2,6-Dichloro-5-fluoro-4-methyl-3-pyridinecarboxylic acid;2,6-Dichloro-5-fluoro-4-methylnicotinic acid
• CAS NO: 132195-42-7
• Molecular Formula: C₇H₄Cl₂FNO₂
• Molecular Weight: 224.02
• Mol File: 132195-42-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 355℃
• Flash Point: 168℃
• Appearance: /
• Density: 1.605
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 1.21±0.38(Predicted)
• CAS DataBase Reference: 2,6-Dichloro-5-fluoro-4-methylpyridine-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Dichloro-5-fluoro-4-methylpyridine-3-carboxylic acid(132195-42-7)
• EPA Substance Registry System: 2,6-Dichloro-5-fluoro-4-methylpyridine-3-carboxylic acid(132195-42-7)

Safety Data

• Hazardous Substances Data: 132195-42-7(Hazardous Substances Data)

Usage

General Description

2,6-Dichloro-5-fluoro-4-methylpyridine-3-carboxylic acid is a chemical compound with the molecular formula C7H5Cl2FNO2. It is a synthetic organic compound and is classified as a pyridine carboxylic acid. This chemical compound is commonly used in the pharmaceutical industry as an intermediate in the synthesis of various drugs, particularly in the development of antimicrobial and antibacterial agents. Its structure and properties make it suitable for use in the creation of pharmaceutical compounds that target specific biological processes and pathways. Additionally, it is also used in research and development for the creation of new drugs and medical treatments.

Upstream product

• 82671-06-5 2,6-dichloro-5-fluoro-3-pyridinecarboxylic acid 
• 74-88-4 methyl iodide 

Downstream Products

• 132195-69-8 7-<(3S)-3-amino-1-pyrrolidynyl>-6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-5-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid 
• 138668-56-1 7-(2,5-Diaza-bicyclo[2.2.2]oct-2-yl)-1-(2,4-difluoro-phenyl)-6-fluoro-5-methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid 
• 138668-55-0 7-(1R,4R)-2,5-Diaza-bicyclo[2.2.1]hept-2-yl-1-(2,4-difluoro-phenyl)-6-fluoro-5-methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid 
• 132195-60-9 7-((S)-3-Amino-pyrrolidin-1-yl)-1-(2,4-difluoro-phenyl)-6-fluoro-5-methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester 
• 138668-53-8 1-(2,4-Difluoro-phenyl)-6-fluoro-5-methyl-4-oxo-7-piperazin-1-yl-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid 
• 132195-65-4 7-((3S)-3-amino-1-pyrrolidinyl)-1,4,-dihydro-1-(2,4-difluorophenyl)-6-fluoro-5-methyl-4-oxo-1,8-napthyridine-3-carboxylic acid 
• 132195-48-3 7-((S)-3-Amino-pyrrolidin-1-yl)-6-fluoro-1-(4-fluoro-phenyl)-5-methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester 
• 132195-58-5 (Z)-2-(2,6-Dichloro-5-fluoro-4-methyl-pyridine-3-carbonyl)-3-(2,4-difluoro-phenylamino)-acrylic acid ethyl ester 
• 132195-59-6 7-chloro-6-fluoro-5-phenyl-1-(2,4-difluorophenyl)-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid ethyl ester 
• 132195-46-1 (Z)-2-(2,6-Dichloro-5-fluoro-4-methyl-pyridine-3-carbonyl)-3-(4-fluoro-phenylamino)-acrylic acid ethyl ester 

Relevant articles and documents

Antibacterial compounds

Antibacterials having formula (I) and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates used in the processes, compositions containing the compounds, and methods of prophylaxis and treatment of bacterial infections using the compounds are disclosed.