13220-44-5

Basic information

• Product Name: 3-(4-nitrobenzyl)-1,3-dihydro-2H-indol-2-one
• CAS NO: 13220-44-5
• Molecular Formula: C₁₅H₁₂N₂O₃
• Molecular Weight: 268.2674
• Mol File: 13220-44-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 486.8°C at 760 mmHg
• Flash Point: 248.2°C
• Density: 1.333g/cm³
• Vapor Pressure: 1.26E-09mmHg at 25°C
• Refractive Index: 1.645
• CAS DataBase Reference: 3-(4-nitrobenzyl)-1,3-dihydro-2H-indol-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-nitrobenzyl)-1,3-dihydro-2H-indol-2-one(13220-44-5)
• EPA Substance Registry System: 3-(4-nitrobenzyl)-1,3-dihydro-2H-indol-2-one(13220-44-5)

Safety Data

• Hazardous Substances Data: 13220-44-5(Hazardous Substances Data)

Upstream product

• 59-48-3 2-oxoindole 
• 555-16-8 4-nitrobenzaldehdye 

Downstream Products

• 1606131-14-9 3-(2-nitro-1-phenylethyl)-3-(4-nitrobenzyl)indolin-2-one 
• 1376933-20-8 (R)-3-(4-nitrobenzyl)-3-(phenylthio)indolin-2-one 
• 1304075-28-2 (3R)-3-(4-nitrobenzyl)-3-((1S)-3-oxocyclohexyl)-2-oxoindole 

Relevant articles and documents

Chiral N,N′-Dioxide/Scandium(III)-Catalyzed Asymmetric Alkylation of N-Unprotected 3-Substituted Oxindoles

An efficient enantioselective alkylation of N-unprotected 3-substituted oxindoles was realized by using a chiral N,N′-dioxide/scandium(III) complex as the catalyst. A wide range of 3,3-dialkyl substituted oxindoles with quaternary stereocenters were obtained in high yields and ee values (up to 98% yield and 99% ee). (Figure presented.).