1322091-34-8

Basic information

• Product Name: 1,3-dicyclohexyl-1-(6-fluoro-3-(4-methoxyphenyl)isoquinolin-1-yl)-2-tosylguanidine
• Synonyms: 1,3-dicyclohexyl-1-(6-fluoro-3-(4-methoxyphenyl)isoquinolin-1-yl)-2-tosylguanidine
• CAS NO: 1322091-34-8
• Molecular Weight: 628.811
• Mol File: 1322091-34-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,3-dicyclohexyl-1-(6-fluoro-3-(4-methoxyphenyl)isoquinolin-1-yl)-2-tosylguanidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-dicyclohexyl-1-(6-fluoro-3-(4-methoxyphenyl)isoquinolin-1-yl)-2-tosylguanidine(1322091-34-8)
• EPA Substance Registry System: 1,3-dicyclohexyl-1-(6-fluoro-3-(4-methoxyphenyl)isoquinolin-1-yl)-2-tosylguanidine(1322091-34-8)

Safety Data

• Hazardous Substances Data: 1322091-34-8(Hazardous Substances Data)

Upstream product

• 1322091-24-6 4-fluoro-2-((4-methoxyphenyl)ethynyl)benzaldehyde 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 538-75-0 dicyclohexyl-carbodiimide 

Relevant articles and documents

An expeditious approach to 1-(isoquinolin-1-yl)guanidines via a three-component reaction of 2-alkynylbenzaldehyde, sulfonohydrazide, with carbodiimide

A small library of 1-(isoquinolin-1-yl)guanidine is constructed efficiently via a silver triflate-catalyzed three-component reaction of 2-alkynylbenzaldehyde, sulfonohydrazide, with carbodiimide. The preliminary biological screens of these isoquinoline library members have been evaluated, which show promising results as PTP1B inhibitor and HCT-116 inhibitor.