132233-66-0Relevant academic research and scientific papers
Synthesis and Biological Activity of 5-Alkyl-1,7,8-trisubstituted-6-fluoroquinoline-3-carboxylic Acids
Hagen, Susan E.,Domagala, Johan M.,Heifetz, Carl L.,Johnson, Judith
, p. 1155 - 1161 (2007/10/02)
A series of 5-alkyl-1,7,8-trisubstituted-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids was prepared and evaluated for in vitro and in vivo antibacterial activity.When compared to the 5-hydrogen analogues, the presence of the 5-methyl group enhanc
Quinoline antibacterial compounds
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, (2008/06/13)
Quinoline compounds having the formula: STR1 wherein R is a phenyl group or an aromatic heterocyclic group, Z is an aliphatic heterocyclic group or an amine, and R1 is hydrogen or a carboxy-protecting group. The compounds here disclosed have an
