132233-73-9Relevant articles and documents
Synthesis and Biological Activity of 5-Alkyl-1,7,8-trisubstituted-6-fluoroquinoline-3-carboxylic Acids
Hagen, Susan E.,Domagala, Johan M.,Heifetz, Carl L.,Johnson, Judith
, p. 1155 - 1161 (1991)
A series of 5-alkyl-1,7,8-trisubstituted-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids was prepared and evaluated for in vitro and in vivo antibacterial activity.When compared to the 5-hydrogen analogues, the presence of the 5-methyl group enhanc