132235-43-9

Basic information

• Product Name: (2S)-2-Methyl-2-PyrrolidinecarboxaMide
• Synonyms: (2S)-2-Methyl-2-PyrrolidinecarboxaMide;(S)-2-Methylpyrrolidine-2-carboxaMide
• CAS NO: 132235-43-9
• Molecular Formula: C₆H₁₂N₂O
• Molecular Weight: 128.17228
• Mol File: 132235-43-9.mol
• Article Data: 7

Chemical Properties

• Melting Point: 45-46 °C
• Boiling Point: 286.4±29.0 °C(Predicted)
• Appearance: /
• Density: 1.054±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 16.21±0.20(Predicted)
• CAS DataBase Reference: (2S)-2-Methyl-2-PyrrolidinecarboxaMide(CAS DataBase Reference)
• NIST Chemistry Reference: (2S)-2-Methyl-2-PyrrolidinecarboxaMide(132235-43-9)
• EPA Substance Registry System: (2S)-2-Methyl-2-PyrrolidinecarboxaMide(132235-43-9)

Safety Data

• Hazardous Substances Data: 132235-43-9(Hazardous Substances Data)

Usage

General Description

"(2S)-2-Methyl-2-PyrrolidinecarboxaMide" is a chemical compound with the molecular formula C7H13NO. It is a cyclic secondary amine and is commonly used as a chiral building block in organic synthesis. (2S)-2-Methyl-2-PyrrolidinecarboxaMide is often utilized in the pharmaceutical industry for the production of various medications, particularly for the development of drugs with potential biological activity. Additionally, it has been studied for its potential applications in the fields of materials science and catalysis. Its unique structure and properties make it a valuable compound in the development of diverse chemical and pharmaceutical products.

Upstream product

• 1031890-09-1 benzyl (S)-2-carbamoyl-2-methylpyrrolidine-1-carboxylate 
• 132235-40-6 (1'R,2S,2'S,5'R)-1-<(2-isopropyl-5-methylcyclohexyl)oxymethoxy>-2-methyl-2-pyrrolidine carboxamide 
• 6931-10-8 3,4-dihydro-5-methyl-2H-pyrrole 1-oxide 
• 63399-71-3 (S)-1-((benzyloxy)carbonyl)-2-methylpyrrolidine-2-carboxylic acid 
• 63399-73-5 α-methyl-L-proline hydrobromide 
• 132235-36-0 (1'R,2S,2'S,5'R)-1-<(2-isopropyl-5-methylcyclohexyl)oxymethoxy>-2-methyl-2-pyrrolidinecarbonitrile 
• 1163706-66-8 (S)-2-methyl-pyrrolidine-2-carboxylic acid butyl ester 
• 848488-83-5 DL-(α-methyl)proline amide 
• 1415303-32-0 (2S,1'S)-N-(1'-phenylethyl)-α-methylprolinamide (S)-mandelic acid salt 
• 5891-21-4 5-chloro-2-pentanone 
• 1361112-89-1 2-methylpyrrolidine-2-carboxamide hydrochloride 
• 42457-13-6 2-cyano-2-methylpyrrolidine 

Downstream Products

• 1163705-29-0 (S)-2-methyl-pyrrolidine-1,2-dicarboxylic acid 2-amide 1-({5-[2-(2,6-dichloro-benzyl)-pyrimidin-4-yl]-4-methyl-thiazol-2-yl}-amide) 
• 1163705-28-9 (S)-2-methyl-pyrrolidine-1,2-dicarboxylic acid 2-amide 1-({5-[2-(2-fluoro-phenyl)-pyrimidin-4-yl]-4-methyl-thiazol-2-yl}-amide) 
• 1163705-24-5 (S)-2-methyl-pyrrolidine-1,2-dicarboxylic acid 2-amide 1-{[5-(2-benzyl-pyrimidin-4-yl)-4-methyl-thiazol-2-yl]-amide} 
• 1163705-34-7 (S)-2-methyl-pyrrolidine-1,2-dicarboxylic acid 2-amide 1-{[5-(3-tert-butyl-phenyl)-4-methyl-thiazol-2-yl]-amide} 
• 1163705-64-3 (S)-2-methyl-pyrrolidine-1,2-dicarboxylic acid 2-amide 1-[(5-{2-[2-(4-methoxy-phenyl)-1,1-dimethyl-ethyl]-pyrimidin-4-yl}-4-methyl-thiazol-2-yl)-amide] 
• 1163705-69-8 (S)-2-methyl-pyrrolidine-1,2-dicarboxylic acid 2-amide 1-({4-methyl-5-[2-(1-phenyl-cyclopentyl)-pyrimidin-4-yl]-thiazol-2-yl}-amide) 
• 1163705-70-1 (S)-2-methyl-pyrrolidine-1,2-dicarboxylic acid 2-amide 1-({5-[2-(1,1-dimethyl-2-p-tolyl-ethyl)-pyrimidin-4-yl]-4-methyl-thiazol-2-yl}-amide) 
• 1163705-63-2 (S)-2-methyl-pyrrolidine-1,2-dicarboxylic acid 2-amide 1-({5-[2-(4-methoxy-phenoxymethyl)-pyrimidin-4-yl]-4-methyl-thiazol-2-yl}-amide) 
• 42856-71-3 (S)-2-methylpyrrolidine-2-carboxylic acid 

Relevant articles and documents

Α-substd. provitamin optically active production of phosphorus

PROBLEM TO BE SOLVED: To provide an industrial method practically suitable for producing an optically active α-substituted prolines with short process and mild conditions.SOLUTION: A method of producing an optically active α-substituted prolines (6) includes (d) a step of obtaining an optically active N, α-substituted prolines (5) by hydrolysis of an optically active N, α-substituted proline amides (4), and (e) a step of obtaining an optically active α-substituted prolines (6) by eliminating the optically active N, and a protective group Rof the α-substituted prolines (5).

2-Carboxamide Cycloamino Ureas

The present invention relates to compounds of formula I and salts thereof, wherein the substituents are as defined in the description, to compositions and use of the compounds in the treatment of diseases ameloriated by inhibition of phosphatidylinositol

Organic Compounds

The present invention relates to compounds of formula I and its salts, wherein the substituents are as defined in the description, to compositions and use of the compounds in the treatment of diseases ameloriated by inhibition of phosphatidylinositol 3-kinase.