63399-71-3 Usage
Chemical structure
A proline molecule with an additional benzyloxy carbonyl group and a methyl group attached to the alpha carbon.
Composition
The compound is composed of carbon (C), hydrogen (H), oxygen (O), and nitrogen (N) atoms.
Stereochemistry
The compound is an L-proline derivative, which means it has a specific three-dimensional arrangement of atoms.
Functional groups
The compound contains an amide group, an ester group, and an alkyl group.
Protecting group
The benzyloxy carbonyl group serves as a protecting group for the proline molecule, allowing for selective manipulation during chemical reactions.
Methyl group
The presence of a methyl group on the proline molecule may influence its conformation and properties.
Applications
The compound is commonly used in organic synthesis and as a building block in pharmaceutical research and development.
Potential uses
It has potential applications in drug discovery and development processes, particularly in the development of new drugs and bioactive compounds.
Solubility
The compound is likely soluble in organic solvents such as methanol, ethanol, and dimethyl sulfoxide (DMSO), but its solubility in water may be limited.
Stability
The compound is stable under normal laboratory conditions, but it may be sensitive to hydrolysis or other chemical reactions that could remove the protecting group or alter the molecule's structure.
Check Digit Verification of cas no
The CAS Registry Mumber 63399-71-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,3,9 and 9 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 63399-71:
(7*6)+(6*3)+(5*3)+(4*9)+(3*9)+(2*7)+(1*1)=153
153 % 10 = 3
So 63399-71-3 is a valid CAS Registry Number.
63399-71-3Relevant academic research and scientific papers
Azetidine-derived amino acids versus proline derivatives. Alternative trends in reverse turn induction
Baeza, Jose Luis,Gerona-Navarro, Guillermo,De Vega, M. Jesus Perez,Garcia-Lopez, M. Teresa,Gonzalez-Muniz, Rosario,Martin-Martinez, Mercedes
, p. 1704 - 1715 (2008/09/20)
(Figure Presented) The influence of 2-alkyl-2-carboxyazetidines (Aze) on the 3D structure of model tetrapeptides R2CO-2-R1Aze-L- Ala-NHMe has been analyzed by molecular modeling, 1H NMR, and FT-IR studies. The conformation
NOVEL AMINOPYRIMIDINE DERIVATIVES AS PLK1 INHIBITORS
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Page/Page column 62, (2008/12/07)
The present invention relates to a compound represented by Formula [I]: or a pharmaceutically acceptable salt or ester thereof, wherein R1 and R2, which may be the same or different, are each a hydrogen atom, a halogen atom, a lower
Preparation and Use of Chloromethyl (-)-Menthyl Ether in the Synthesis of Optically Pure α-Branched α-Amino Nitriles
Shatzmiller, Shimon,Dolithzky, Ben-Zion,Bahar, Eliezer
, p. 375 - 379 (2007/10/02)
The synthesis of optically pure chloromethyl (-)-menthyl ether (2b) and its use in the synthesis of di-(-)-menthyl acetal (-)-menthyl (+)-menthyl acetals are described.The diastereomeric mixed acetals 7a,b and 8a,b are easily obtainable from the nitrones 5 and 6, KCN and 2b.The mixture of diastereomers are separated into the pure components 7a, 7b and 8a, 8b by simple silica gel column chromatography.Hydrolysis of these products (H2O2/Na2CO3, ultrasound) followed by N-O cleavage affords the heterocyclic α-methyl-α-amino amides 11a, 11b and 12a, 12b.These are subsequently hydrolyzed to give the corresponding α-methyl-α-amino acids with S and R configuration, respectively.
