13225-61-1

Basic information

• Product Name: 1,7-diphenyl-4-oxahepta-1,6-diyne
• Synonyms: 1,7-diphenyl-4-oxahepta-1,6-diyne
• CAS NO: 13225-61-1
• Molecular Weight: 246.309
• Mol File: 13225-61-1.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 1,7-diphenyl-4-oxahepta-1,6-diyne(CAS DataBase Reference)
• NIST Chemistry Reference: 1,7-diphenyl-4-oxahepta-1,6-diyne(13225-61-1)
• EPA Substance Registry System: 1,7-diphenyl-4-oxahepta-1,6-diyne(13225-61-1)

Safety Data

• Hazardous Substances Data: 13225-61-1(Hazardous Substances Data)

Upstream product

• 1504-58-1 3-Phenyl-2-propyn-1-ol 
• 591-50-4 iodobenzene 
• 914650-12-7 (3-(but-2-yn-1-yloxy)prop-1-yn-1-yl)benzene 
• 6921-27-3 dipropargyl ether 
• 6261-22-9 pent-2-yn-1-ol 
• 53877-63-7 (3-(prop-2-ynyloxy)prop-1-ynyl)benzene 

Downstream Products

• 13225-65-5 4-phenyl-1,3-dihydro{naphtho-[2,3-c]}furan 
• 1046132-04-0 C₂₂H₁₇NO₃ 
• 1217489-53-6 C₂₈H₂₄O₂ 
• 1228814-56-9 C₂₄H₂₄O 
• 61051-02-3 4,5,7-triphenyl-1,3-dihydroisobenzofuran 
• 1273555-14-8 tricarbonyl(2,4-bis(phenyl)-7-oxybicyclo[3.3.0]hepta-1,4-dien-3-one)iron 
• 2579-22-8 Phenylpropargyl aldehyde 

Relevant articles and documents

Alumina-Mediated π-Activation of Alkynes

The ability to induce powerful atom-economic transformation of alkynes is the key feature of carbophilic π-Lewis acids such as gold- and platinum-based catalysts. The unique catalytic activity of these compounds in electrophilic activations of alkynes is explained through relativistic effects, enabling efficient orbital overlapping with π-systems. For this reason, it is believed that noble metals are indispensable components in the catalysis of such reactions. In this study, we report that thermally activated γ-Al2O3activates enynes, diynes, and arene-ynes in a manner enabling reactions that were typically assigned to the softest π-Lewis acids, while some were known to be triggered exclusively by gold catalysts. We demonstrate the scope of these transformations and suggest a qualitative explanation of this phenomenon based on the Dewar-Chatt-Duncanson model confirmed by density functional theory calculations.

A Ruthenium Complex-Catalyzed Cyclotrimerization of Halodiynes with Nitriles. Synthesis of 2- and 3-Halopyridines

Monohalo- and dihalodiynes efficiently undergo [2+2+2] cyclotrimerization with nitriles in the presence of a catalytic amount of the ruthenium complex Cp*RuCl(cod) (10 mol%) to afford the corresponding halopyridines under ambient conditions in good isolated yields (up to 90%). The halopyridines are formed as two separable regioisomers. This is the first example of a direct synthesis of halopyridines from haloalkynes and nitriles. (Figure presented.) .

Bifunctional (cyclopentadienone)iron-tricarbonyl complexes: Synthesis, computational studies and application in reductive amination

Reductive amination under hydrogen pressure is a valuable process in organic chemistry to access amine derivatives from aldehydes or ketones. Knoelker's complex has been shown to be an efficient iron catalyst in this reaction. To determine the influence of the substituents on the cyclopentadienone ancillary ligand, a series of modified Knoelker's complexes was synthesised and fully characterised. These complexes were also transformed into their analogous acetonitrile iron-dicarbonyl complexes. Catalytic activities of these complexes were evaluated and compared in a model reaction. The scope of this reaction is also reported. For mechanistic insights, deuterium-labelling experiments and DFT calculations were undertaken and are also presented. Festival of amination: Two series of modified Knoelker's complexes were synthesised and applied in the reductive amination of various carbonyl derivatives with primary or secondary amines (see scheme, TIPS = triisopropylsilyl). For a mechanistic insight, deuterium-labelling experiments and DFT calculations were undertaken and are also presented. Copyright