132256-80-5Relevant academic research and scientific papers
Synthesis of 2-aroylquinoxalines, 1-aroylphthalazines, and 4-aroylcinnolines; an aroylation method using arenecarbaldehydes catalyzed by azolium salt1
Miyashita, Akira,Suzuki, Yumiko,Iwamoto, Ken-Ichi,Oishi, Etsuo,Higashino, Takeo
, p. 405 - 413 (2007/10/03)
2-Aroylquinoxalines (5,6), 1-aroylphthalazines (10,11), and 4-aroylcinnolines (13) were synthesized by using arenecarbaldehydes (2) in the presence of an azolium salt (1) in moderate to good yields. 1,3-Dimethylimidazolium iodide (1a) and sodium sulfinate
REACTION OF METHOXY-N-HETEROAROMATICS WITH PHENYLACETONITRILE UNDER BASIC CONDITIONS
Yamanaka, Hiroshi,Ohba, Setsuya
, p. 895 - 909 (2007/10/02)
The monomethoxyl derivatives of various ?-electron deficient N-heteroaromatics reacted with phenylacetonitrile in tetrahydrofuran in the presence of sodium hydride to give α-phenyl-N-heteroareneacetonitriles in the yields ranging from 45 to 78percent.On the contrary, the reaction of these methoxyl derivatives with ethyl cyanoacetate or malononitrile under similar conditions was restricted within narrow limits.The synthesis of benzoyl-N-heteroaromatics by the air-oxidation of α-phenyl-N-hetroareneacetonitriles was described additionally.
