1322681-63-9

Upstream product

• 104-87-0 4-methyl-benzaldehyde 
• 56686-16-9 5-bromo-2,4-dimethoxypyrimidine 
• 1322681-61-7 (5-bromo-2,6-dimethoxypyrimidin-4-yl)(p-tolyl)methanone 
• 1066-54-2 trimethylsilylacetylene 
• 1322681-59-3 (5-bromo-2,6-dimethoxypyrimidin-4-yl)(p-tolyl)methanol 

Downstream Products

• 1339872-39-7 dimethyl 4,6,10-trimethoxy-11-methyl-1-p-tolyl-15-oxa-3,5-diaza-tricyclo[6.6.1.0(2,7)]pentadeca-2⁽⁷⁾,3,5,8,10,13-hexaene-13,14-dicarboxylate 
• 1339872-34-2 (5-ethynyl-2,6-dimethoxypyrimidin-4-yl)p-tolylmethanone 

Relevant academic research and scientific papers

One-pot three-component synthesis of quinoxaline, quinazoline, and phenazine ring systems using fischer carbene complexes

One-pot, three-component synthesis of nitrogen-containing polycyclic heterocycles bearing two nitrogen atoms such as quinoxaline, quinazoline, and phenazine derivatives by the coupling of appropriate vicinal alkynylheteroaryl carbonyl derivatives with Fischer carbene complexes and dienophiles has been investigated. This involves the generation of furo[3,4-b]pyrazines, furo[3,4-d]pyrimidines, and furo[3,4-b]quinoxalines as transient intermediates, which were trapped with suitable Diels-Alder dienophiles in an inter- or intramolecular fashion. Georg Thieme Verlag Stuttgart New York.

Annulation of furan-bridged 10-membered rings on N-heterocycles through [8+2] cycloaddition of dienylazaisobenzofurans and dimethyl acetylenedicarboxylate

One-pot three-component coupling of o-alkynylheteroaryl carbonyl derivatives with α,β-unsaturated Fischer carbene complexes and dimethyl acetylenedicarboxylate leading to the synthesis of heterocyclic analogues of furanophane derivatives has been explored