1322748-56-0Relevant articles and documents
Inhibition of nonmammalian glycosidases by azetidine iminosugars derived from stable 3,5-Di-O-triflates of pentoses
Lenagh-Snow, Gabriel M. J.,Araujo, Noelia,Jenkinson, Sarah F.,Rutherford, Catherine,Nakagawa, Shinpei,Kato, Atsushi,Yu, Chu-Yi,Weymouth-Wilson, Alexander C.,Fleet, George W. J.
, p. 5834 - 5837 (2012/01/06)
Efficient ring closure of stable crystalline 3,5-di-O-triflates of pentofuranosides with amines to form azetidines allowed preliminary evaluation of four-ring iminosugars as glycosidase inhibitors; significant and specific inhibition of nonmammalian α-glucosidases is shown by l-xylo- and l-arabino-iminosugar azetidines.