132278-77-4

Upstream product

• 558-13-4 carbon tetrabromide 
• 2439-43-2 (2RS)-2-phenylbutanal 

Downstream Products

• 59409-55-1 (1-ethyl-1,2-propadienyl)benzene 
• 132278-82-1 Benzyl-(1-ethyl-1-phenyl-prop-2-ynyl)-methyl-amine 
• 1367368-61-3 trimethyl(3-phenylpent-1-yn-1-yl)silane 

Relevant academic research and scientific papers

Direct Synthesis of α-Allenols from TMS-Protected Alkynes and Aldehydes Mediated by Tetrabutylammonium Fluoride

A unique chemoselective synthesis of α-allenic alcohols is presented. Tetrabutylammonium fluoride (TBAF) mediated this transformation under mild reaction conditions. A range of functional groups is well-tolerated in this reaction, while affording adducts

2-Propynylamines from 1,1-Dibromo-1-alkenes

Easily accessible 1,1-dibromo-1-alkenes react with primary or secondary amines in a complex series of reactions to give directly N-substituted or N,N-disubstituted (1-Alkyl-1-aryl-2-propynyl)amines 5 in useful yields.This simple method avoids the isolation of intermediates (bromoacetylenes or bromoallenes) and makes a series of 2-propynylamines with an acetylenic hydrogen available.